红霉素

Erythromycin (订货以英文为准)

编号:E105345
CAS号:114-07-8
分子式:C37H67NO13
分子量:733.93
货号 品牌 包装 目录价 您的价格 库存 数量 购买
E105345-25g 阿拉丁 25g ¥167.90
E105345-5g 阿拉丁 5g ¥60.90
E105345-100g 阿拉丁 100g ¥472.90
E105345-1g 阿拉丁 1g ¥31.90
E105345-500g 阿拉丁 500g ¥1938.90
产品名称 Erythromycin
中文名称 红霉素
CAS号 114-07-8
分子式(M.F.) C37H67NO13
分子量(M.W.) 733.93
储存条件 充氩
熔点138-140°C
旋光率-74 ° (C=2, EtOH)
敏感性对湿度敏感
溶解性熔于乙醇、甲醇、丙酮、氯仿、乙腈和乙酸乙酯,中等程度溶于醚、二氯甲烷和乙酸戊酯。难溶于水。微有引湿性,无臭,味苦。遇酸不稳定。水中溶解度:+/- 3 MG/ML。
存贮条件充氩保存
密度1.2000
应用A macrolide antibiotic protein synthesis inhibitor.Erythromycin is an antibiotic produced by growth of certain strains of Streptomyces erythreus. This product is composed largely of erythromycin A with small amounts of erythromycins B and C and is recommended for concentration at 100 mg/L. Concentrations between 50 and 200 mg/L have also proven effective in controlling bacterial growth. Erythromycin has been used as a motilin receptor agonist, to block respiratory glycoconjugate secretion in human airways in vitro, and for selecting plasmid-cured and recombinant lactococcus lactis MG1363 strains.
产品介绍Erythromycin is a potent macrolide inhibitor of CYP3A4 with antiinflammatory and prokinetic properties. Macrolides belong to a group of antibiotics that bind to the 50S ribosomal subunit and inhibit protein synthesis. Erythromycin is derived from Streptomyces erythreus and has been shown to inhibit NF-κB transcriptional activation, which leads to the inhibition of cytokine gene expression of IL-8 and lL-6. This mechanism was shown to occur via calcineruin-independent signaling T lymphocytes.
备注此产品所配溶液37°C只能保存3天,因此其储存溶液必须2-8°C保存.This product is soluble in water at 2 mg/mL, with a 0.067% solution in water yielding a pH of 8.0-10.5. It is also soluble in ethanol at 50 mg/mL, yielding a clear, colorless to faint yellow solution. It is freely soluble in alcohol, acetone, chloroform, acetonitrile and ethyl acetate but forms salts with acids. All solutions should be protected from light.
生化机理在转肽步骤抑制延长期,靠结合到核糖体上抑制细菌蛋白合成,对细菌诱发红霉素抗性。抗菌谱: 革兰氏阴性和阳性细菌。属大环内酯抗生素(Macrolide antibiotic)
别名红霉素;红霉素碱;(-)-Erythromycin ;Abomacetin
UN代码2811
搜索质检报告(COA)
搜索MSDS
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