VU 0364770,mGlu4受体的正变构调节剂

VU 0364770 (订货以英文为准)

编号:V129525
CAS号:61350-00-3
分子式:C12H9CLN2O
分子量:232.67
货号 品牌 包装 目录价 您的价格 库存 数量 购买
V129525-50mg 阿拉丁 50mg ¥288.90
V129525-10mg 阿拉丁 10mg ¥193.90
V129525-250mg 阿拉丁 250mg ¥1404.90
V129525-100mg 阿拉丁 100mg ¥610.90
产品名称 VU 0364770
中文名称 VU 0364770,mGlu4受体的正变构调节剂
CAS号 61350-00-3
分子式(M.F.) C12H9CLN2O
分子量(M.W.) 232.67
储存条件 -20°C储存
溶解性DMSO 47 mg/mL Water <1 mg/mL Ethanol 47 mg/mL
存贮条件储存温度-20°C
应用A postitive allosteric modulator of mGluR-4
产品介绍VU 0364770 is a positive allosteric modulator(PAM) of mGlu4 with EC50 of 1.1 μM, exhibits insignificant activity at 68 other receptors, including other mGlu subtypes.
备注VU 0364770 is a positive allosteric modulator(PAM) of mGlu4 with EC50 of 1.1 μM, exhibits insignificant activity at 68 other receptors, including other mGlu subtypes.
生化机理VU 0364770 is a positive allosteric modulator of mGluR-4 (EC50 = 290 nM in mGluR-4-expressing HEK 293 cells). VU 0364770 acts in many other ways such as the reversal of haloperidol-induced catalepsy in rats; and in rodent models of Parkinson's disease, preventing attentional deficit and forelimb asymmetry.
别名N-(3-氯苯基)-2-吡啶甲酰胺;N-(3-Chlorophenyl)-2-pyridinecarboxamide
搜索质检报告(COA)
搜索MSDS
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