| 溶解性 | DMSO 47 mg/mL Water <1 mg/mL Ethanol 47 mg/mL |
| 存贮条件 | 储存温度-20°C |
| 应用 | A postitive allosteric modulator of mGluR-4 |
| 产品介绍 | VU 0364770 is a positive allosteric modulator(PAM) of mGlu4 with EC50 of 1.1 μM, exhibits insignificant activity at 68 other receptors, including other mGlu subtypes. |
| 备注 | VU 0364770 is a positive allosteric modulator(PAM) of mGlu4 with EC50 of 1.1 μM, exhibits insignificant activity at 68 other receptors, including other mGlu subtypes. |
| 生化机理 | VU 0364770 is a positive allosteric modulator of mGluR-4 (EC50 = 290 nM in mGluR-4-expressing HEK 293 cells). VU 0364770 acts in many other ways such as the reversal of haloperidol-induced catalepsy in rats; and in rodent models of Parkinson's disease, preventing attentional deficit and forelimb asymmetry. |
| 别名 | N-(3-氯苯基)-2-吡啶甲酰胺;N-(3-Chlorophenyl)-2-pyridinecarboxamide |
VU 0364770,mGlu4受体的正变构调节剂
VU 0364770 （订货以英文为准）
编号：V129525
CAS号：61350-00-3
分子式：C12H9CLN2O
分子量：232.67
| 产品名称 | VU 0364770 |
| 中文名称 | VU 0364770,mGlu4受体的正变构调节剂 |
| CAS号 | 61350-00-3 |
| 分子式（M.F.） | C12H9CLN2O |
| 分子量（M.W.） | 232.67 |
| 储存条件 | -20°C储存 |
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