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Alternate Text一般危化品

丹磺胺

Dansylcadaverine （订货以英文为准）

编号：D131032
CAS号：10121-91-2
分子式：C17H25N3O2S
分子量：335.46
货号 品牌 包装 目录价 您的价格 库存 数量 购买
D131032-250mg 阿拉丁 250mg ¥398.90
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D131032-50mg 阿拉丁 50mg ¥99.90
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D131032-1g 阿拉丁 1g ¥1280.90
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D131032-10mg 阿拉丁 10mg ¥39.90
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产品名称 Dansylcadaverine
中文名称 丹磺胺
CAS号 10121-91-2
分子式（M.F.） C17H25N3O2S
分子量（M.W.） 335.46
储存条件 -20°C储存;充氩
敏感性对空气敏感
溶解性10 mg/mL Methanol
存贮条件储存温度-20°C 充氩保存
应用A fluorescent amine probeDansylcadaverine in methanol has a reported λex of 335 nm and λem of 512 nm. It has been used:· as an endocytosis inhibitor in human proximal tubular HK-2 cells, mouse J774A.1 macrophages and human A549 epithelial cells· to label autophagic vacuoles in cardiomyocytes for fluorescence microscopy studies· in monodansylcadaverine (MDC) staining of fibroblasts in Ankylosing spondylitis (AS) samples
产品介绍Dansylcadaverine is a fluorescent amine probe, which is believed to directly inhibit vesicular transport. Studies indicate that Dansylcadaverine can act as a marker used to study autophagy in the cytoplasm and vacuoles of plants and mammalian cells. Dansylcadaverine functions by marking the autophagosomes, which allows researchers to follow the molecular components of the process throughout. It is known that the specificity of Dansylcadaverine towards mammalian autophagosomes is due to ion trapping through the acidic compartments of autophagosomes. In addition, Dansylcadaverine has biological applications in measuring cardiac autophagic flux, studying Parkinson's disease, peritoneal ovarian tumor dissemination, and respiratory diseases. This fluorescent tag is preferred over other due to its specificity and simplicity in detecting autophagic vesicles, which requires a brief exposure to the compound compared to previous methods.
生化机理自发荧光染料丹酰尸胺或单丹磺酰尸胺（MDC）通常用于监测自噬。 由于离子捕获和与膜脂质的特异性相互作用的组合，单丹磺酰尸胺优先在自噬泡中积累。
别名丹酰尸胺;N-丹酰-1,5-戊二胺;N-(5-氨基戊基)-5-(二甲基氨基)萘-1-磺酰胺;N-(5-Amino-pentyl)-5-di-methyl-amino-naphtha-lene-1-sulfon-amide; N-(Dimethyl-amino-naphtha-lene-sulfonyl)-1,5-pentane-diamine Monodansyl cadaverine
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