别名 | 4-(2,5-二氧代四氢呋喃-3-基)-萘满-1,2-二甲酸酐;4-(2,5-Dioxotetrahydrofuran-3-yl)-tetralin-1,2-dicarboxylic Anhydride |
4-(2,5-二氧代四氢呋喃-3-基)-1,2,3,4-四氢萘-1,2-二甲酸酐
4-(2,5-Dioxotetrahydrofuran-3-yl)-1,2,3,4-tetrahydronaphthalene-1,2-dicarboxylic Anhydride (订货以英文为准)
编号:D155084
CAS号:13912-65-7
分子式:C16H12O6
分子量:300.26
产品名称 | 4-(2,5-Dioxotetrahydrofuran-3-yl)-1,2,3,4-tetrahydronaphthalene-1,2-dicarboxylic Anhydride |
中文名称 | 4-(2,5-二氧代四氢呋喃-3-基)-1,2,3,4-四氢萘-1,2-二甲酸酐 |
CAS号 | 13912-65-7 |
分子式(M.F.) | C16H12O6 |
分子量(M.W.) | 300.26 |
储存条件 | 充氩 |
Reaxys-RN | 10604867 |
技术规格
Background: | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by HDAC5 belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. |
Applications: | WB, IHC |
Name of antibody: | HDAC5 (Phospho-Ser498) |
Immunogen: | Synthetic peptide of human HDAC5 (Phospho-Ser498) |
Full name: | histone deacetylase 5 (Phospho-Ser498) |
Synonyms: | HD5; NY-CO-9 |
SwissProt: | Q9UQL6 |
IHC positive control: | Human breast carcinoma |
IHC Recommend dilution: | 50-100 |
WB Predicted band size: | 122 kDa |
WB Positive control: | 293 cells untreated or treated with serum starvation |
WB Recommended dilution: | 500-1000 |
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