| 别名 | 1,2-二溴-4,5-(亚甲二氧基)苯;4,5-二溴-1,2-亚甲二氧基苯;1,2-Dibromo-4,5-(methylenedioxy)benzene;4,5-Methylenedioxy-1,2-dibromobenzene |
5,6-二溴-1,3-苯并二恶茂
5,6-Dibromo-1,3-benzodioxole （订货以英文为准）
编号：D154173
CAS号：5279-32-3
分子式：C7H4BR2O2
分子量：279.91
| 产品名称 | 5,6-Dibromo-1,3-benzodioxole |
| 中文名称 | 5,6-二溴-1,3-苯并二恶茂 |
| CAS号 | 5279-32-3 |
| 分子式（M.F.） | C7H4BR2O2 |
| 分子量（M.W.） | 279.91 |
| Reaxys-RN | 1875750 |
| 标识符号 | https://www.aladdin-e.com/images/ghs/ghs07.jpg |
| 信号词 | Warning |
| 危害声明 | H315,H319,H335 |
| 警示性声明 | P261,P305+P351+P338 |
| 个人防护设备 | dust mask type N95 (US), Eyeshields, Gloves |
| RTECS | UR2845000 |
| WGK德国 | 3 |
| 风险声明 (欧洲) | R36/37/38 |
| 安全声明（欧洲） | S26;S37/39 |
| 危害码（欧洲） | Xi |
技术规格
| Background: | The protein encoded by this gene is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. This protein is preferentially expressed in cells of myeloid lineage. It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation. This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system. The PX domain of this protein can bind phospholipid products of the PI(3) kinase, which suggests its role in PI(3) kinase-mediated signaling events. The phosphorylation of this protein was found to negatively regulate the enzyme activity. Alternatively spliced transcript variants encoding distinct isoforms have been observed. |
| Applications: | WB |
| Name of antibody: | NCF4 |
| Immunogen: | Fusion protein of human NCF4 |
| Full name: | neutrophil cytosolic factor 4, 40kDa |
| Synonyms： | MGC3810; NCF; P40PHOX; SH3PXD4 |
| SwissProt: | Q15080 |
| WB Predicted band size: | 39 kDa |
| WB Positive control: | K562 cells |
| WB Recommended dilution: | 500-2000 |
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