| 溶解性 | Soluble in DMSO: >10 mg/mL and Water: <2 mg/mL |
| 存贮条件 | 储存温度2-8℃ |
| 应用 | A c-Myc inhibitor and apoptosis inducer. |
| 产品介绍 | 10058-F4是一种c-Myc抑制剂，特异性抑制c-Myc-Max相互作用，且抑制c-Myc靶基因表达的转录激活。 |
| 备注 | 10058-F4 is a c-Myc inhibitor that specificallly inhibits the c-Myc-Max interaction and prevents transactivation of c-Myc target gene expression. |
| 生化机理 | 10058-F4 is a c-Myc inhibitor that prevents c-Myc/Max dimerization. c-Myc is a proto-oncogene that plays an important role in cell proliferation, differentiation, and apoptosis. 10058-F4 has been shown to arrest cell growth at G0/G1 phase. Experiments show that 10058-F4 is a c-Myc inhibitor that prevents c-Myc/Max dimerization. c-Myc is a proto-oncogene that plays an important role in cell proliferation, differentiation, and apoptosis. 10058-F4 has been shown to arrest cell growth at G0/G1 phase. Experiments show that extended exposure to 10058-F4 causes apoptosis via upregulation of Bax, expression of cytoplasmic Cytochrome C, down-regulation of Bcl-2, and cleavage of caspase-3,-7, and -9. This compound has been found to also upregulate cyclin-dependent kinase inhibitors, p21 and p27. |
| 别名 | 5-[(4-乙基苯基)亚甲基]-2-硫代-4-噻唑烷酮;5-(4-乙基苯亚甲基)绕丹宁;5-[(4-Ethylphenyl)methylene]-2-thioxo-4-thiazolidinone |
5-(4-乙基苯亚甲基)绕丹宁
10058-F4 （订货以英文为准）
编号：F129209
CAS号：403811-55-2
分子式：C12H11NOS2
分子量：249.35
| 货号 | 品牌 | 包装 | 目录价 | 您的价格 | 库存 | 数量 | 购买 |
|---|---|---|---|---|---|---|---|
| F129209-25mg | 阿拉丁 | 25mg | ¥457.90 |
|
| 产品名称 | 10058-F4 |
| 中文名称 | 5-(4-乙基苯亚甲基)绕丹宁 |
| CAS号 | 403811-55-2 |
| 分子式（M.F.） | C12H11NOS2 |
| 分子量（M.W.） | 249.35 |
| 储存条件 | 2-8°C储存 |
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