概述
Fusion protein corresponding to a region derived from 895-1094 amino acids of human AP3B1
技术规格
| Full name: | adaptor related protein complex 3 subunit beta 1 |
| Synonyms: | PE; HPS; HPS2; ADTB3; ADTB3A |
| Swissprot: | O00203 |
| Gene Accession: | BC038444 |
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | Escherichia coli |
| Tags: | His tag C-Terminus, GST tag N-Terminus |
| Background: | This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is part of the heterotetrameric AP-3 protein complex which interacts with the scaffolding protein clathrin. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 2. Two transcript variants encoding different isoforms have been found for this gene. |
小艺 