概述
Fusion protein corresponding to C terminal 250 amino acids of human ACOX1
技术规格
| Full name: | Acyl-CoA oxidase 1, palmitoyl |
| Synonyms: | ACOX; SCOX; PALMCOX |
| Swissprot: | Q15067 |
| Gene Accession: | BC010425 |
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | Escherichia coli |
| Tags: | His tag C-Terminus, GST tag N-Terminus |
| Background: | The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified. |
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