概述
Full length of human SARS-CoV-2 N protein (1-419 aa)
技术规格
| Full name: | Severe acute respiratory syndrome coronavirus 2 nucleocapsid protein |
| Synonyms: | COVID-19; 2019-nCoV; SARS-CoV-2; Nucleocapsid protein; Nucleoprotein; 新型冠状病毒 |
| Swissprot: | P0DTC9 |
| Gene Accession: | MN908947 |
| Purity: | >90%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | Escherichia coli |
| Tags: | 6×His tag N-terminals |
| Species: | SARS-CoV-2/2019-nCoV |
| Molecular mass: | 48.0 kDa |
| Research areas: | Microbiology |
| Activity: | 1.Measured by its binding ability in a functional ELISA. Immobilized SARS-CoV-2-N at 2 μg/ml can bind SARS-CoV-2-N Antibody (Catalog number: D141004), the EC50 of SARS-CoV-2-N protein is 1.368 -1.804 ng/ml. 2.Measured by its binding ability in a functional ELISA. Immobilized SARS-CoV-2-N at 2 μg/ml can bind SARS-CoV-2-N Antibody (Catalog number: D141005), the EC50 of SARS-CoV-2-N protein is 4.267-5.568 ng/ml. |
| Reconstitution: | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference. |
| Background: | Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication (By similarity). May modulate transforming growth factor-beta signaling by binding host smad3 (By similarity). |
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