| 溶解性 | DMSO 89 mg/mL Water <1 mg/mL Ethanol 45 mg/mL |
| 存贮条件 | 储存温度-20°C |
| 备注 | MK-0752 is a moderately potent γ-secretase inhibitor, which reduces Aβ40 production with IC50 of 5 nM. Phase 1/2. |
| 生化机理 | MK-0752 is a potent gamma secretase (γ-secretase) inhibitor in clinical development with an IC50 of 5 nM for Aβ40 in human SH-SY5Y cells. MK-0752 is useful in treatment of Alzheimer’s disease |
| 别名 | 3-((1r,4s)-4-(4-chlorophenylsulfonyl)-4-(2,5-difluorophenyl)cyclohexyl)propanoic acid;3-((1r,4s)-4-(4-chlorophenylsulfonyl)-4-(2,5-difluorophenyl)cyclohexyl)propanoic acid |
MK-0752,γ-secretase（γ-分泌酶）抑制剂
MK-0752 （订货以英文为准）
编号：M126008
CAS号：471905-41-6
分子式：C21H21CLF2O4S
分子量：442.91
| 产品名称 | MK-0752 |
| 中文名称 | MK-0752,γ-secretase（γ-分泌酶）抑制剂 |
| CAS号 | 471905-41-6 |
| 分子式（M.F.） | C21H21CLF2O4S |
| 分子量（M.W.） | 442.91 |
| 储存条件 | -20°C储存 |
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