| 沸点 | 286°C |
| 熔点 | 109-111°C |
| 折光率 | 1.4303 |
| 敏感性 | 对湿度敏感 |
| 溶解性 | Soluble in water (2.4 mg/ml at 20 °C), ethanol (5%), DMSO, methanol (70 mg/ml), and alcohol. |
| 存贮条件 | 密封保存。 |
| 密度 | 0.8210 |
| 应用 | An antiinflammatory compound |
| 产品介绍 | Azelaic acid is a dicarboxylic acid that exhibits anti-inflammatory activity. It is known for it’s anti acne activity in vitro. Azelaic acid directly inhibits kallikrein 5 (KLK5), downregulating expression of KLK5, toll-like receptor 2 (TLR 2), and cathelicidin, and suppresses activity of serine proteases in vitro, in vivo, and in clinical settings. In PUFA-treated fibroblasts, azelaic acid decreases generation of ROS and upregulates expression of antioxidative enzymes, inhibiting cell damage; agonist activity at PPARν is thought to drive these effects. Azelaic acid also inhibits proliferation of melanocytes. This compound displays antiacne and anticancer potential as well, inhibiting the proliferation of cutaneous melanoma due to suppression of mitochondrial oxidoreductive activity and DNA synthesis. |
| 别名 | 杜鹃花酸;1,7-壬二酸;庚烷-1,7-二羟酸;王二酸;1,7-庚二甲酸;Nonanedioic acid;1,7-heptanedicarboxylic acid; |
壬二酸
Azelaic acid （订货以英文为准）
编号：A108439
CAS号：123-99-9
分子式：C9H16O4
分子量：188.22
| 产品名称 | Azelaic acid |
| 中文名称 | 壬二酸 |
| CAS号 | 123-99-9 |
| 分子式（M.F.） | C9H16O4 |
| 分子量（M.W.） | 188.22 |
搜索质检报告(COA)
搜索MSDS
相关产品
党沛 
