| 沸点 | 86°C/8mmHg |
| 折光率 | 1.5950 |
| 敏感性 | 对湿度敏感 |
| 存贮条件 | 充氩保存 |
| 密度 | 1.3490 |
| 应用 | 2,4-Difluorophenyl isothiocyanate may be used in the synthesis of the following 2-(4-(4-X-phenylsulfonyl)benzoyl)-N-(2,4-difluorophenyl)hydrazinecarbothioamides:· N-(2,4-difluorophenyl)-2-(4-(phenylsulfonyl)benzoyl)hydrazinecarbothioamide· 2-(4-(4-chlorophenylsulfonyl)benzoyl)-N-(2,4-difluorophenyl)hydrazinecarbothioamide· 2-(4-(4-bromophenylsulfonyl)benzoyl)-N-(2,4-difluorophenyl)hydrazinecarbothioamide |
| 别名 | 异硫氰酸2,4-二氟苯酯;2,4-二氟苯异硫氰酸酯;Isothiocyanic Acid 2,4-Difluorophenyl Ester |
2,4-二氟异硫氰酸苯酯
2,4-Difluorophenyl isothiocyanate （订货以英文为准）
编号：D122880
CAS号：141106-52-7
分子式：C7H3F2NS
分子量：171.17
| 产品名称 | 2,4-Difluorophenyl isothiocyanate |
| 中文名称 | 2,4-二氟异硫氰酸苯酯 |
| CAS号 | 141106-52-7 |
| MDL编码 | MFCD00041044 |
| 分子式（M.F.） | C7H3F2NS |
| 分子量（M.W.） | 171.17 |
| 储存条件 | 充氩 |
| Reaxys-RN | 1740199 |
| 标识符号 | https://www.aladdin-e.com/images/ghs/ghs02.jpg,https://www.aladdin-e.com/images/ghs/ghs05.jpg,https://www.aladdin-e.com/images/ghs/ghs07.jpg |
| 信号词 | Danger |
| 危害声明 | H225,H302+H312+H332,H314,H335 |
| 警示性声明 | P210,P261,P280,P305+P351+P338,P310 |
| 个人防护设备 | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
| WGK德国 | 3 |
| 闪点（摄氏） | -15°C |
| 风险声明 (欧洲) | R11;R20/21/22;R34;R36/37 |
| 安全声明（欧洲） | S16;S26;S27;S33;S36/37/39;S45 |
| 危害码（欧洲） | F;C |
技术规格
| Background: | cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. This subunit has been shown to regulate protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER). |
| Applications: | ELISA, WB, IHC |
| Name of antibody: | PRKAR2A |
| Immunogen: | Fusion protein of human PRKAR2A |
| Full name: | protein kinase, cAMP-dependent, regulatory subunit type II alpha |
| Synonyms: | PKR2; PRKAR2 |
| SwissProt: | P13861 |
| ELISA Recommended dilution: | 5000-10000 |
| IHC positive control: | Human breast cancer and human esophagus cancer |
| IHC Recommend dilution: | 35-200 |
| WB Predicted band size: | 46 kDa |
| WB Positive control: | HEPG2 cell and Human testis tissue lysates |
| WB Recommended dilution: | 500-2000 |
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