JNJ-7706621,泛CDK抑制剂

JNJ-7706621 (订货以英文为准)

编号:J125527
CAS号:443797-96-4
分子式:C15H12F2N6O3S
分子量:394.36
货号 品牌 包装 目录价 您的价格 库存 数量 购买
J125527-2mg 阿拉丁 2mg ¥555.90
J125527-10mg 阿拉丁 10mg ¥1760.90
J125527-5mg 阿拉丁 5mg ¥925.90
J125527-50mg 阿拉丁 50mg ¥4263.90
J125527-100mg 阿拉丁 100mg ¥7518.90
产品名称 JNJ-7706621
中文名称 JNJ-7706621,泛CDK抑制剂
CAS号 443797-96-4
分子式(M.F.) C15H12F2N6O3S
分子量(M.W.) 394.36
储存条件 -20°C储存;充氩
溶解性DMSO 79 mg/mL Water <1 mg/mL Ethanol <1 mg/mL
存贮条件储存温度-20°C
备注JNJ-7706621 is pan-CDK inhibitor with the highest potency on CDK1/2 with IC50 of 9 nM/4 nM and showing >6-fold selectivity for CDK1/2 than CDK3/4/6. It also potently inhibits Aurora A/B and has no activity on Plk1 and Wee1.
生化机理JNJ-7706621 is a dual cyclin-dependent kinases and aurora kinases inhibitor with IC50 of 9 and 11 nM for CDK1/Cyclin B and aurora-A, respectively.
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