溶解性 | DMSO 79 mg/mL Water <1 mg/mL Ethanol <1 mg/mL |
存贮条件 | 储存温度-20°C |
备注 | JNJ-7706621 is pan-CDK inhibitor with the highest potency on CDK1/2 with IC50 of 9 nM/4 nM and showing >6-fold selectivity for CDK1/2 than CDK3/4/6. It also potently inhibits Aurora A/B and has no activity on Plk1 and Wee1. |
生化机理 | JNJ-7706621 is a dual cyclin-dependent kinases and aurora kinases inhibitor with IC50 of 9 and 11 nM for CDK1/Cyclin B and aurora-A, respectively. |
JNJ-7706621,泛CDK抑制剂
JNJ-7706621 (订货以英文为准)
编号:J125527
CAS号:443797-96-4
分子式:C15H12F2N6O3S
分子量:394.36
产品名称 | JNJ-7706621 |
中文名称 | JNJ-7706621,泛CDK抑制剂 |
CAS号 | 443797-96-4 |
分子式(M.F.) | C15H12F2N6O3S |
分子量(M.W.) | 394.36 |
储存条件 | -20°C储存;充氩 |
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