| 沸点 | 164°C(lit.) |
| 别名 | ; |
3-(二甲氨基)吡咯烷
3-(Dimethylamino)pyrrolidine （订货以英文为准）
编号：D155175
CAS号：69478-75-7
分子式：C6H14N2
分子量：114.19
| 产品名称 | 3-(Dimethylamino)pyrrolidine |
| 中文名称 | 3-(二甲氨基)吡咯烷 |
| CAS号 | 69478-75-7 |
| 分子式（M.F.） | C6H14N2 |
| 分子量（M.W.） | 114.19 |
| 储存条件 | 充氩 |
| Reaxys-RN | 471182 |
| 标识符号 | https://www.aladdin-e.com/images/ghs/ghs02.jpg,https://www.aladdin-e.com/images/ghs/ghs05.jpg,https://www.aladdin-e.com/images/ghs/ghs07.jpg |
| 信号词 | Danger |
| 危害声明 | H226,H302,H315,H318,.H335 |
| 警示性声明 | P261,P280,P305+P351+P338 |
| 个人防护设备 | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
| WGK德国 | 2 |
| 闪点（摄氏） | 51°C |
| 风险声明 (欧洲) | R10;R22;R37/38;R41 |
| 安全声明（欧洲） | S26;S39 |
| 危害码（欧洲） | Xn |
技术规格
| Background: | This gene is a target gene of the transcription factor tumor protein p53. The encoded protein is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53, as part of an autoregulatory negative feedback loop. Overexpression of this gene can result in excessive inactivation of tumor protein p53, diminishing its tumor suppressor function. This protein has E3 ubiquitin ligase activity, which targets tumor protein p53 for proteasomal degradation. This protein also affects the cell cycle, apoptosis, and tumorigenesis through interactions with other proteins, including retinoblastoma 1 and ribosomal protein L5. More than 40 different alternatively spliced transcript variants have been isolated from both tumor and normal tissues |
| Applications: | WB, IHC, IF |
| Name of antibody: | MDM2 (phospho-Ser166) |
| Immunogen: | Synthetic peptide of human MDM2 (phospho-Ser166) |
| Full name: | MDM2 oncogene, E3 ubiquitin protein ligase (phospho-Ser166) |
| Synonyms： | HDMX; hdm2; ACTFS |
| SwissProt: | Q00987 |
| IHC positive control: | Human breast carcinoma |
| IHC Recommend dilution: | 50-100 |
| WB Predicted band size: | 90 kDa |
| WB Positive control: | 293 cells treated with Hydroxyurea |
| WB Recommended dilution: | 500-1000 |
| IF Positive control: | Hela cells |
| IF Recommended dilution | 100-200 |
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