| 别名 | ;['6-Methyl-1,4-dihydroquinoxaline-2,3-dione', '6-Methylquinoxaline-2,3-diol'] |
1,4-二氢-6-甲基喹喔啉-2,3-二酮
1,4-Dihydro-6-methylquinoxaline-2,3-dione （订货以英文为准）
编号：D155127
CAS号：6309-61-1
分子式：C9H8N2O2
分子量：176.17
| 产品名称 | 1,4-Dihydro-6-methylquinoxaline-2,3-dione |
| 中文名称 | 1,4-二氢-6-甲基喹喔啉-2,3-二酮 |
| CAS号 | 6309-61-1 |
| 分子式（M.F.） | C9H8N2O2 |
| 分子量（M.W.） | 176.17 |
技术规格
| Background: | Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation. |
| Applications: | WB, IF |
| Name of antibody: | H2AFX (Phospho-Ser139) |
| Immunogen: | Synthetic peptide of human H2AFX (Phospho-Ser139) |
| Full name: | H2A histone family, member X (Phospho-Ser139) |
| Synonyms： | H2AX; H2A.X; H2A/X |
| SwissProt: | P16104 |
| WB Predicted band size: | 15 kDa |
| WB Positive control: | HT29 cells treated with UV |
| WB Recommended dilution: | 500-1000 |
| IF Positive control: | Hela cells |
| IF Recommended dilution | 100-200 |
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