| 熔点 | 198-200 °C |
| 敏感性 | 对热敏感,对空气敏感 |
| 溶解性 | Soluble in water (Partly miscible), DMSO (25 mg/mL warm), ethanol (5 mg/mL warm), chloroform, ethyl acetate, DMF (~20 mg/mL), and 1:1 solution of DMSO:PBS(pH 7.2) (~0.5 mg/mL). |
| 存贮条件 | 储存温度 2-8°C ,充氩保存 |
| 应用 | An inhibitor of prostaglandin synthesis as well as Cox-1 and Cox-2. |
| 产品介绍 | Piroxicam 是一种非选择性COX抑制剂,IC50为6 mM。 |
| 备注 | Piroxicam (Feldene) is a non-selective COX inhibitor with an IC50 of 6 mM. |
| 生化机理 | Piroxicam is an effective and potent inhibitor of prostaglandin synthesis and a Cox-1 and Cox-2 inhibitor. Studies show that Piroxicam blocks release of platelet ADP, and inhibits Cox-1 (human prostaglandin H synthase isozyme-1, hPGHS-1) more potently than Cox-2 (hPGHS-2). Piroxicam is also a non-steroidal compound with anti-inflammatory properties. |
| 别名 | 2-甲基-4-羟基-N-(2-吡啶基)-2H-1,2-苯并噻嗪-3-甲酰胺-1,1-二氧化物;吡啶苯噻酰胺 ;吡氧噻嗪;炎痛喜康;吡罗昔康;Piroxicamum;Larapam;Feldene;4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-Dioxide; 4-Hydroxy-2-methyl-3-(2-pyridylcarbamoyl)-2H-1,2-benzothiazine 1,1-Dioxide |
吡罗昔康
Piroxicam (订货以英文为准)
编号:P129294
CAS号:36322-90-4
分子式:C15H13N3O4S
分子量:331.35
| 产品名称 | Piroxicam |
| 中文名称 | 吡罗昔康 |
| CAS号 | 36322-90-4 |
| 分子式(M.F.) | C15H13N3O4S |
| 分子量(M.W.) | 331.35 |
| 储存条件 | 2-8°C储存;充氩 |
| 标识符号 | https://www.aladdin-e.com/images/ghs/ghs06.jpg,https://www.aladdin-e.com/images/ghs/ghs08.jpg |
| 信号词 | Danger |
| 危害声明 | H301-H312-H315-H319-H332-H334-H335 |
| 警示性声明 | P261-P280-P301 + P310-P305 + P351 + P338-P342 + P311 |
| 个人防护设备 | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
| WGK德国 | 3 |
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