溶解性 | DMSO |
存贮条件 | 储存温度-20°C |
产品介绍 | CGI-1746是Btk抑制剂。 |
生化机理 | CGI-1746 is a small-molecule Bruton's tyrosine kinase (Btk) inhibitor chemotype with a new binding mode that stabilizes an inactive nonphosphorylated enzyme conformation. CGI-1746 has exquisite selectivity for Btk and inhibits both auto- and transphosphorylation steps necessary for enzyme activation. CGI-1746 is useful for heumatoid Arthritis |
别名 | CGI1746;CGI 1746; N-(3-(4,5-二氢-4-甲基-6-((4-(4-吗啉基羰基)苯基)氨基)-5-氧代-2-吡嗪基)-2-甲基苯基)-4-(叔丁基)苯甲酰胺;;CGI1746; CGI 1746;n-(3-(4,5-dihydro-4-methyl-6-((4-(4-morpholinylcarbonyl)phenyl)amino)-5-oxo-2-pyrazinyl)-2-methylphenyl)-4-(tert-butyl)benzamide |
CGI-1746
CGI-1746 (订货以英文为准)
编号:C127514
CAS号:910232-84-7
分子式:C34H37N5O4
分子量:579.69
产品名称 | CGI-1746 |
中文名称 | CGI-1746 |
CAS号 | 910232-84-7 |
分子式(M.F.) | C34H37N5O4 |
分子量(M.W.) | 579.69 |
储存条件 | -20°C储存 |
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