CGI-1746

CGI-1746 (订货以英文为准)

编号:C127514
CAS号:910232-84-7
分子式:C34H37N5O4
分子量:579.69
货号 品牌 包装 目录价 您的价格 库存 数量 购买
C127514-50mg 阿拉丁 50mg ¥2619.90
C127514-5mg 阿拉丁 5mg ¥522.90
C127514-10mg 阿拉丁 10mg ¥948.90
产品名称 CGI-1746
中文名称 CGI-1746
CAS号 910232-84-7
分子式(M.F.) C34H37N5O4
分子量(M.W.) 579.69
储存条件 -20°C储存
溶解性DMSO
存贮条件储存温度-20°C
产品介绍CGI-1746是Btk抑制剂。
生化机理CGI-1746 is a small-molecule Bruton's tyrosine kinase (Btk) inhibitor chemotype with a new binding mode that stabilizes an inactive nonphosphorylated enzyme conformation. CGI-1746 has exquisite selectivity for Btk and inhibits both auto- and transphosphorylation steps necessary for enzyme activation. CGI-1746 is useful for heumatoid Arthritis
别名CGI1746;CGI 1746; N-(3-(4,5-二氢-4-甲基-6-((4-(4-吗啉基羰基)苯基)氨基)-5-氧代-2-吡嗪基)-2-甲基苯基)-4-(叔丁基)苯甲酰胺;;CGI1746; CGI 1746;n-(3-(4,5-dihydro-4-methyl-6-((4-(4-morpholinylcarbonyl)phenyl)amino)-5-oxo-2-pyrazinyl)-2-methylphenyl)-4-(tert-butyl)benzamide
搜索质检报告(COA)
搜索MSDS
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