熔点 | 204°C-206°C |
敏感性 | 对光线敏感 |
溶解性 | Soluble to 10 mM in Ethanol and to 10 mM in DMSO |
存贮条件 | 储存温度-20°C,充氩储存 |
应用 | Ionomycin is more effective than A23187 as a Ca++ionophore.Ionomycin is used in research on Ca++ transport across biological membranes; Ionomycin induces apoptotic degeneration of embryonic cortical neurons |
产品介绍 | Ionomycin free acid is an antibiotic selective calcium ionophore, which can extract calcium ions from aqueous phase to organic phase. In addition, Ionomycin free acid acts as a transport carrier, which helps transport cations across solvent barriers. Studies indicate that this antibiotic can transport other ions such as Mg, Sr, and Ba with a weaker affinity. It is known that Ionomycin free acid is produced by Streptomyces conglobatus. Furthermore, Ionomycin free acid is a beneficial tool in research to raise intracellular calcium levels. Also this antibiotic can be used to study the calcium transport across the plasma membrane. |
生化机理 | Ionomycin is a Ca2+ ionophore that is more effective than A23187 as a mobile ion carrier for Ca2+. It is non-fluorescent. It induces apoptotic degeneration of embryonic cortical neurons. |
别名 | ;(4R,6S,8S,10Z,12R,14R,16E,18S,19S,20R,21S)-11,19,21-Trihydroxy-22-{(2S,2'S,5S,5'R)-5'-[(1S)-1-hydroxyethyl]-2,5'-dimethyloctahydro-2,2'-bifuran-5-yl}-4,6,8,12,14,18,20-heptamethyl-9-oxo-10,16-docosadi enoic acid; SQ 23377 |
离子霉素
Ionomycin (free acid) (订货以英文为准)
编号:I139530
CAS号:56092-81-0
分子式:C41H72O9
分子量:709.01
产品名称 | Ionomycin (free acid) |
中文名称 | 离子霉素 |
CAS号 | 56092-81-0 |
分子式(M.F.) | C41H72O9 |
分子量(M.W.) | 709.01 |
储存条件 | 避光;-20°C储存;充氩 |
标识符号 | https://www.aladdin-e.com/images/ghs/ghs08.jpg |
信号词 | Danger |
危害声明 | H317,H334 |
警示性声明 | P261,P272,P280,P285,P302+P352,P304+P341,P321,P333+P313,P342+P311,P363,P501 |
个人防护设备 | Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter |
WGK德国 | 3 |
安全声明(欧洲) | 22,24/25 |
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