沸点 | 225°C(lit.) |
熔点 | 52-56℃ |
别名 | 2,4-二氯-6-甲基苯酚;4,6-二氯-2-甲基苯酚;4,6-二氯甲酚;2,4-Dichloro-6-methylphenol |
4,6-二氯邻甲酚
4,6-Dichloro-o-cresol (订货以英文为准)
编号:D155343
CAS号:1570-65-6
分子式:C7H6CL2O
分子量:177.03
产品名称 | 4,6-Dichloro-o-cresol |
中文名称 | 4,6-二氯邻甲酚 |
CAS号 | 1570-65-6 |
分子式(M.F.) | C7H6CL2O |
分子量(M.W.) | 177.03 |
技术规格
Background: | The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
Applications: | WB, IHC |
Name of antibody: | STAT3(Ab-727) |
Immunogen: | Synthetic peptide of human STAT3 |
Full name: | signal transducer and activator of transcription 3 |
Synonyms: | APRF; HIES; ADMIO; ADMIO1 |
SwissProt: | P40763 |
IHC positive control: | Human breast carcinoma |
IHC Recommend dilution: | 50-100 |
WB Predicted band size: | 88 kDa |
WB Positive control: | Hela cells |
WB Recommended dilution: | 500-1000 |
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