| 溶解性 | DMSO 91 mg/mL Water <1 mg/mL Ethanol 6 mg/mL |
| 存贮条件 | 储存温度-20°C |
| 备注 | GDC-0349 is a potent and selective ATP-competitive inhibitor of mTOR with Ki of 3.8 nM, 790-fold inhibitory effect against PI3Kα and other 266 kinases. Phase 1. |
| 生化机理 | GDC-0349 is a potent mTOR inhibitor. GDC-0349 has entered in a phase I clinical trials in the treatment of Solid Tumors or Non Hodgkin's Lymphoma. |
| 别名 | RG7603;Urea, N-ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]-;RG7603;Urea, N-ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]- |
GDC-0349
GDC-0349 （订货以英文为准）
编号：G128080
CAS号：1207360-89-1
分子式：C24H32N6O3
分子量：452.55
| 产品名称 | GDC-0349 |
| 中文名称 | GDC-0349 |
| CAS号 | 1207360-89-1 |
| 分子式（M.F.） | C24H32N6O3 |
| 分子量（M.W.） | 452.55 |
| 储存条件 | -20°C储存 |
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