BMS-927711,CGRP受体拮抗剂

BMS-927711 (订货以英文为准)

编号:B125641
CAS号:1289023-67-1
分子式:C28H28F2N6O3
分子量:534.56
货号 品牌 包装 目录价 您的价格 库存 数量 购买
B125641-100mg 阿拉丁 100mg ¥13903.90
B125641-10mg 阿拉丁 10mg ¥2243.90
B125641-25mg 阿拉丁 25mg ¥5005.90
B125641-50mg 阿拉丁 50mg ¥8150.90
B125641-5mg 阿拉丁 5mg ¥1383.90
产品名称 BMS-927711
中文名称 BMS-927711,CGRP受体拮抗剂
CAS号 1289023-67-1
分子式(M.F.) C28H28F2N6O3
分子量(M.W.) 534.56
储存条件 避光;-20°C储存
溶解性DMSO
存贮条件储存温度-20°C
生化机理Calcitonin gene-related peptide (CGRP) is closely involved in the cascade of molecular events leading to migraine painful crisis. New CGRP-R antagonist, such as BMS-927711, is in the pipeline and its developments will outline the future of this drug class. BMS-927711 has good oral bioavailability in rat and cynomolgus monkey, attractive overall preclinical properties, and shows dose-dependent activity in a primate model of CGRP-induced facial blood flow. BMS-927711 is presently in phase II clinical trials.
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