德立替尼

E-3810 (订货以英文为准)

编号:E127640
CAS号:1058137-23-7
分子式:C26H25N3O4
分子量:443.49
货号 品牌 包装 目录价 您的价格 库存 数量 购买
E127640-10mg 阿拉丁 10mg ¥1618.90
E127640-5mg 阿拉丁 5mg ¥988.90
E127640-50mg 阿拉丁 50mg ¥6199.90
E127640-25mg 阿拉丁 25mg ¥4028.90
E127640-100mg 阿拉丁 100mg ¥8548.90
E127640-1mg 阿拉丁 1mg ¥376.90
产品名称 E-3810
中文名称 德立替尼
CAS号 1058137-23-7
分子式(M.F.) C26H25N3O4
分子量(M.W.) 443.49
储存条件 -20°C储存
溶解性DMSO
存贮条件储存温度-20°C
生化机理E-3810, a novel dual inhibitor targeting human vascular endothelial growth factor receptors (VEGFRs) and fibroblast growth factor receptors (FGFRs) with antiangiogenic activity. VEGFR/FGFR dual kinase inhibitor E-3810 inhibits VEGFR-1, -2, -3 and FGFR-1, -2 kinases in the nM range, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation, and the induction of tumor cell death. Both VEGFRs and FGFRs belong to the family of receptor tyrosine kinases that may be upregulated in various tumor cell types.
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