| 溶解性 | DMSO |
| 存贮条件 | 储存温度-20°C |
| 产品介绍 | Olcegepant(BIBN 4096; BIBN 4096BS)是非肽类CGRP1受体选择性拮抗剂，IC50为 0.03 nM。 |
| 生化机理 | Olcegepant(BIBN-4096; BIBN-4096BS) inhibits the release and action of Calcitonin Gene-Related Peptide (CGRP).Olcegepant is useful for treatment of acute attacks of migraine.Olcegepant exhibiting a favorable biological profile was selected for initial clinical trials. A proof of concept study indicated that intravenous application of 19 was effective in the treatment of acute migraine headache. |
| 别名 | N-[2-[5-氨基-1(S)-[4-(4-吡啶基)哌嗪-1-甲酰基]戊基氨基]-1(R)-(3,5-二溴-4-羟基苄基)-2-氧代乙基]-4-(2-氧代-1,2,3,4-四氢喹唑啉-3-基)哌啶-1-甲酰胺;BIBN-4096; BIBN-4096BS;BIBN4096BS; BIBN 4096BS; N-[2-[5-Amino-1(S)-[4-(4-pyridinyl)piperazin-1-ylcarbonyl]pentylamino]-1(R)-(3,5-dibromo-4-hydroxybenzyl)-2-oxoethyl]-4-(2-oxo-1,2,3,4-tetrahydroquinazolin-3-yl)piperidine-1-carboxamide |
Olcegepant,CGRP-1受体拮抗剂
Olcegepant （订货以英文为准）
编号：O126666
CAS号：204697-65-4
分子式：C38H47BR2N9O5
分子量：869.65
| 产品名称 | Olcegepant |
| 中文名称 | Olcegepant,CGRP-1受体拮抗剂 |
| CAS号 | 204697-65-4 |
| 分子式（M.F.） | C38H47BR2N9O5 |
| 分子量（M.W.） | 869.65 |
| 储存条件 | -20°C储存 |
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