卡托普利

Captopril (订货以英文为准)

编号:C129108
CAS号:62571-86-2
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C129108-100g 阿拉丁 100g ¥759.90
C129108-25g 阿拉丁 25g ¥345.90
C129108-5g 阿拉丁 5g ¥152.90
C129108-500g 阿拉丁 500g ¥1872.90
C129108-1g 阿拉丁 1g ¥70.90
产品名称 Captopril
中文名称 卡托普利
CAS号 62571-86-2
储存条件 -20°C储存;充氩
熔点106°C
旋光率-127.5°
敏感性对空气敏感
溶解性Soluble in water (160 mg/ml) at 25 °C, sesame and corn oils (<1 mg/ml) at 25 °C, methanol (>100 mg/ml), ethanol (>100 mg/ml), isopropanol (>100 mg/ml), chloroform (>100 mg/ml), and dichloromethane (>100 mg/ml).
存贮条件储存温度 -20°C; 充氩保存
应用Captopril是一种血管紧张素转换酶(ACE)抑制剂,IC50为6 nM。
产品介绍Captopril is a reversible and competitive inhibitor of leukotriene A4 hydrolase (LTA4H; IC50 = 11μM). Captopril has been shown to be an inhibitor of angiotensin converting enzyme-1 (ACE1), but not ACE2 (IC50 = 22 nM). Captopril demonstrates noncompetitive inhibition of tyrosinase monophenolase activity and competitive inhibition of diphenolase activity. Captopril has also been shown to inhibit the formation of angiotensin II, a bioactive peptide that stimulates angiogenesis and increases microvessel density.
备注Captopril is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 6 nM.
生化机理血管紧张素转换酶抑制剂。抑制血管紧张素 II 的形成,血管紧张素 II 是生物活性多肽,可促进血管生成并增加微血管密度。
别名卡托普利;N-[(S)-3-巯基-2-甲基丙酰基]-L-脯氨酸;(S)-1-(3-巯基-2-甲基-1-氧代丙基)-L-脯氨酸;巯甲丙脯酸;1-((2S)-2-甲基-3-巯基-1-氧代丙基)-L-脯氨酸;Capoten; Cesplon; L-Captopril;N-[(S)-3-Mercapto-2-methylpropionyl]-L-proline;(S)-(-)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline ;(S)-(-)-1-(3-Mercapto-2-methylpropionyl)-L-proline
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