熊果酸

Ursolic acid (订货以英文为准)

编号:U107243
CAS号:77-52-1
分子式:C30H48O3
分子量:456.70
货号 品牌 包装 目录价 您的价格 库存 数量 购买
U107243-1g 阿拉丁 1g ¥97.90
U107243-250mg 阿拉丁 250mg ¥59.90
U107243-5g 阿拉丁 5g ¥270.90
U107243-25g 阿拉丁 25g ¥826.90
产品名称 Ursolic acid
中文名称 熊果酸
CAS号 77-52-1
MDL编码 MFCD00009621
分子式(M.F.) C30H48O3
分子量(M.W.) 456.70
储存条件 2-8°C储存
熔点283-285°C
溶解性Soluble in ethanol (5 mg/ml warm), DMSO (>25 mg/ml warm), and DMF. Insoluble in water.
存贮条件存储温度2-8℃
密度1.0900
应用An anti-angiogenic and anti-proliferative agent
产品介绍存在于天然植物中的一种三萜类化合物。不溶于水,溶于2%酒精的NaOH,溶于热冰醋酸,中度溶于丙酮,微溶于醇、醚、氯仿和二硫化碳。
生化机理Ursolic Acid, a naturally occurring triterpenoid, has been noted to demonstrate anti-angiogenic and anti-proliferative properties. Mechanistic studies suggest that this compound down-regulates MMP-2 and uPA expression in cells via inhibition of Akt, JNK, mammalian target of Rapamycin phosphorylation, and levels of NFκB protein in the nucleus. Other experiments have shown that Ursolic Acid may improve blood glucose, glucose tolerance, insulin tolerance, glycosylated hemoglobin, and plasma leptin levels in diabetic murine models. Additionally, this agent displays a capacity to induce cell cycle arrest and apoptosis through activation of p53 pathway and Bax protein, as well as down-regulation of Bcl-2.
别名乌苏酸;乌索酸;3-羟基-(3β)-乌索-12-烯-28-酸;3β-Hydroxy-12-ursen-28-ic acid
Reaxys-RN81851
Merck Index9326
标识符号https://www.aladdin-e.com/images/ghs/ghs07.jpg
信号词Warning
危害声明H302
个人防护设备dust mask type N95 (US),Eyeshields,Gloves
RTECSJP1192000
WGK德国3
风险声明 (欧洲)R22;R36/37/38
安全声明(欧洲)S26;S37/39
危害码(欧洲)Xn
搜索质检报告(COA)
搜索MSDS
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