| 敏感性 | 对光线敏感 |
| 溶解性 | Soluble in water (9 mg/ml), and 1 M NH4OH (50 mg/ml). |
| 存贮条件 | 储存温度2-8℃ |
| 应用 | A selective antagonist of the NMDA receptor. |
| 产品介绍 | D-AP5 is a selective antagonist of the NMDA receptor. D(-)-2-Amino-5-phosphonovaleric acid is described to antagonize amino acid-induced synaptic excitations, blocking L-aspartate and dorsal root-evoked spinal neuron excitation, without affecting cholinergic excitation induced by exogenous acetylcholine administration. Evoked electrical activity of neurons is suppressed by D(-)-2-Amino-5-phosphonovaleric acid antagonism of motoneuronal depolarizations at the NMDAR. The (+)-stereoisomer of D(-)-2-Amino-5-phosphonovaleric acid demonstrates considerably diminished NMDAR activity as compared to this (-)-isomer. |
| 生化机理 | Anticonvulsant; potent and selective N-methyl-D-aspartate (NMDA) receptor antagonist; active enantiomer of 2-amino-5-phosphonopentanoic acid. |
| 别名 | D-AP5;D-2-氨基-5-膦酰戊酸;D-AP5;D(?)-APV;D-2-Amino-5-phosphonovaleric acid;(2R)-2-ammonio-5-phosphonatopentanoate;D(?)-2-Amino-5-phosphonopentanoic acid;5-Phosphono-D-norvaline |
D-AP5,NMDA谷氨酸位点拮抗剂
(R)-(-)-2-Amino-5-phosphonopentanoic acid （订货以英文为准）
编号：R137370
CAS号：79055-68-8
分子式：C5H12NO5P
分子量：197.13
| 产品名称 | (R)-(-)-2-Amino-5-phosphonopentanoic acid |
| 中文名称 | D-AP5,NMDA谷氨酸位点拮抗剂 |
| CAS号 | 79055-68-8 |
| 分子式（M.F.） | C5H12NO5P |
| 分子量（M.W.） | 197.13 |
| 储存条件 | -20°C储存 |
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