D-64131,微管蛋白聚合抑制剂

D-64131 (订货以英文为准)

编号:D127802
CAS号:74588-78-6
分子式:C16H13NO2
分子量:251.28
货号 品牌 包装 目录价 您的价格 库存 数量 购买
D127802-10mg 阿拉丁 10mg ¥179.90
D127802-50mg 阿拉丁 50mg ¥671.90
D127802-100mg 阿拉丁 100mg ¥1228.90
D127802-5mg 阿拉丁 5mg ¥411.90
D127802-25mg 阿拉丁 25mg ¥754.90
产品名称 D-64131
中文名称 D-64131,微管蛋白聚合抑制剂
CAS号 74588-78-6
MDL编码 MFCD04039791
分子式(M.F.) C16H13NO2
分子量(M.W.) 251.28
储存条件 -20°C储存
溶解性DMSO 100 mM Ethanol 20 mM
存贮条件储存温度-20°C
生化机理D-64131 is a novel inhibitor of Tubulin polymerization that competitively binds with [(3)H]colchicine to αβ-Tubulin. D-64131 is cytotoxic and inhibits tumor cell proliferation in vitro (IC50 = 74 nM). D-64131 prevents growth of tumor models in mice following oral administration in vivo. D-64131 has significant potential in cancer treatment.
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