| 熔点 | 150-152°C |
| 存贮条件 | 储存温度-20°C |
| 应用 | An effective and potent TRPV1 channel antagonist |
| 产品介绍 | 香草素受体1（TRPV1受体）拮抗; BCTC作用于前列腺癌 (PCa) DU145细胞，有效且特异性抑制瞬时受体阳离子通道M成员8(TRPM8)。 |
| 生化机理 | BTBC is an effective and potent transient receptor potential VR1 (vanilloid-1, TRPV1) channel antagonist. VR1 (TRPV1) is a Capsaicin receptor that behaves as a non-selective cation channel that is mainly found in the sensory neurons, and specifically detects painful stimuli, low pH and heat. Studies show that BTBC and Capsazepine both inhibit the activation of rat VR1 (vanilloid receptor 1), induced with acid or Capsaicin. Other VR1 (TRPV1) antagonists include AMG9810 and SB705498. BCTC is an inhibitor of ANKTM1 and TRPM8. |
| 别名 | 4-(3-氯-2-吡啶基)-N-[4-叔丁基苯基]-1-哌嗪甲酰胺;4-(3-Chloro-2-pyridinyl)-N-[4-(1,1-dimethylethyl)phenyl]-1-piperazinecarboxamide |
BCTC,TRPV1的抑制剂
BCTC （订货以英文为准）
编号：B133833
CAS号：393514-24-4
分子式：C20H25N4OCL
分子量：372.89
| 产品名称 | BCTC |
| 中文名称 | BCTC,TRPV1的抑制剂 |
| CAS号 | 393514-24-4 |
| MDL编码 | MFCD08690556 |
| 分子式（M.F.） | C20H25N4OCL |
| 分子量（M.W.） | 372.89 |
| 储存条件 | -20°C储存 |
| 闪点（摄氏） | 45°C(lit.) |
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