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3,3',4,4'-二苯基砜四羧酸二酸酐

3,3',4,4'-Diphenylsulfonetetracarboxylic Dianhydride （订货以英文为准）

编号：D155086
CAS号：2540-99-0
分子式：C16H6O8S
分子量：358.28
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D155086-25g 阿拉丁 25g ¥799.90
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D155086-5g 阿拉丁 5g ¥299.90
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产品名称 3,3',4,4'-Diphenylsulfonetetracarboxylic Dianhydride
中文名称 3,3',4,4'-二苯基砜四羧酸二酸酐
CAS号 2540-99-0
分子式（M.F.） C16H6O8S
分子量（M.W.） 358.28
储存条件 室温;充氩
熔点283°C(lit.)
别名;
Reaxys-RN3670013

技术规格

Background: Involved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Involved in DNA repair via its interaction with BRCA1 and its related phosphorylation by ATM, or via its phosphorylation by ATR. Works as a downstream effector both in the ATM/NBS1 branch and in the ATR/MSH2 branch of S-phase checkpoint.
Applications: WB, IHC
Name of antibody: SMC1A (Phospho-Ser957)
Immunogen: Synthetic peptide of human SMC1A (Phospho-Ser957)
Full name: structural maintenance of chromosomes 1A (Phospho-Ser957)
Synonyms： SMC1; SMCB; CDLS2; SB1.8; SMC1L1; DXS423E; SMC1alpha
SwissProt: Q14683
IHC positive control: Human lung carcinoma
IHC Recommend dilution: 50-100
WB Predicted band size: 143 kDa
WB Positive control: 293 cells untreated or treated with UV
WB Recommended dilution: 500-1000
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