| 溶解性 | Soluble in DMSO (~1.3 mg/ml), DMF (~0.1 mg/ml), and a 1:10 solution of DMSO:PBS(pH7.2) (~0.1 mg/ml). |
| 应用 | Inhibits histone deacetylation. |
| 生化机理 | Suberoyl bis-hydroxamic acid (SBHA) is a Histone deacetylase (HDAC) inhibitor. SBHA inhibits the activity of HDAC1 and HDAC3 with IC50 values of 250 and 300 nM, respectively. SBHA inhibits proliferation, and induces apoptosis in several cancer cell lines. SBHA has been shown to activate Notch signaling in medullary thyroid carcinoma (MTC) cells. |
| 别名 | ;N,N′-Dihydroxyoctanediamide;SBHA;Suberohydroxamic acid;suberic bishydroxamate |
软木肟酸
SuberoylBis-hydroxamicAcid （订货以英文为准）
编号：S135494
CAS号：38937-66-5
分子式：C8H16N2O4
分子量：204.22
| 产品名称 | SuberoylBis-hydroxamicAcid |
| 中文名称 | 软木肟酸 |
| CAS号 | 38937-66-5 |
| 分子式（M.F.） | C8H16N2O4 |
| 分子量（M.W.） | 204.22 |
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