| 溶解性 | DMSO 92 mg/mL Water <1 mg/mL Ethanol 92 mg/mL |
| 存贮条件 | 储存温度-20°C |
| 备注 | BMS-754807 is a potent and reversible inhibitor of IGF-1R/InsR with IC50 of 1.8 nM/1.7 nM, less potent to Met, Aurora A/B, TrkA/B and Ron, and shows little activity to Flt3, Lck, MK2, PKA, PKC etc. Phase 1/2. |
| 生化机理 | BMS-754807 is an orally bioavailable antagonist of human insulin-like growth factor type I receptor (IGF-1R) with potential antineoplastic activity. |
| 别名 | (S)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrrolo[1,2-f][1,2,4]triazin-2-yl)-N-(6-fluoropyridin-3-yl)-2-methylpyrrolidine-2-carboxamide;(S)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrrolo[1,2-f][1,2,4]triazin-2-yl)-N-(6-fluoropyridin-3-yl)-2-methylpyrrolidine-2-carboxamide |
BMS-754807
BMS-754807 （订货以英文为准）
编号：B127174
CAS号：1001350-96-4
分子式：C23H24FN9O
分子量：461.49
| 产品名称 | BMS-754807 |
| 中文名称 | BMS-754807 |
| CAS号 | 1001350-96-4 |
| 分子式（M.F.） | C23H24FN9O |
| 分子量（M.W.） | 461.49 |
| 储存条件 | -20°C储存 |
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