| 别名 | ; |
4-(3,5-二溴苯基)-2,6-二苯基嘧啶
4-(3,5-Dibromophenyl)-2,6-diphenylpyrimidine （订货以英文为准）
编号：D155120
CAS号：607740-08-9
分子式：C22H14BR2N2
分子量：466.17
| 产品名称 | 4-(3,5-Dibromophenyl)-2,6-diphenylpyrimidine |
| 中文名称 | 4-(3,5-二溴苯基)-2,6-二苯基嘧啶 |
| CAS号 | 607740-08-9 |
| MDL编码 | D155120 |
| 分子式（M.F.） | C22H14BR2N2 |
| 分子量（M.W.） | 466.17 |
技术规格
| Background: | Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. May play a role in stabilization of EPO mRNA during hypoxic stress. Isoform Mxi2 activation is stimulated by mitogens and oxidative stress and only poorly phosphorylates ELK1 and ATF2. Isoform Exip may play a role in the early onset of apoptosis. |
| Applications: | WB, IHC |
| Name of antibody: | MAPK14 (Phospho-Thr180) |
| Immunogen: | Synthetic peptide of human MAPK14 (Phospho-Thr180) |
| Full name: | mitogen-activated protein kinase 14 (Phospho-Thr180) |
| Synonyms： | RP1-179N16.5; CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; P38alpha |
| SwissProt: | Q16539 |
| IHC positive control: | Human breast carcinoma |
| IHC Recommend dilution: | 50-100 |
| WB Predicted band size: | 43 kDa |
| WB Positive control: | HT29 cells untreated or treated with UV |
| WB Recommended dilution: | 500-1000 |
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