(-)-表儿茶素没食子酸酯

(-)-Epicatechin gallate (订货以英文为准)

编号:E101659
CAS号:1257-08-5
分子式:C22H18O10
分子量:442.38
货号 品牌 包装 目录价 您的价格 库存 数量 购买
E101659-250mg 阿拉丁 250mg ¥759.90
E101659-1g 阿拉丁 1g ¥2129.90
E101659-100mg 阿拉丁 100mg ¥429.90
E101659-20mg 阿拉丁 20mg ¥566.90
产品名称 (-)-Epicatechin gallate
中文名称 (-)-表儿茶素没食子酸酯
CAS号 1257-08-5
分子式(M.F.) C22H18O10
分子量(M.W.) 442.38
储存条件 2-8°C储存
熔点255°C(lit.)
敏感性对热敏感
溶解性Soluble in water (5 mg/ml) with heat and sonication as needed, yielding a clear, colorless solution, ethanol (~1 mg/ml), methanol (sparingly), DMSO (~10 mg/ml), and DMF (~14 mg/ml).
存贮条件储存温度2-8℃
应用An antioxidant investigated as an adjunct treatment of some methyicillin resistant bacteria.
生化机理(-)Epicatechin gallate is a polyphenol apoptosis inducer in tumor cells commonly found in green tea. Studies suggest that (-)Epicatechin gallate causes anti-proliferative and anti-inflammatory effects on pancreatic ductal adenocarcinoma cells. Alternate studies show that (-)Epicatechin gallate can suppress H2O2-induced genotoxicity in vitro in C6 astroglial cells. In contrast at high concentrations polyphenols are shown to reverse the genoprotective effects that they produce at low concentrations. Furthermore, (-)Epicatechin gallate can inhibit the development of mouse blastocysts via apoptosis. Studies indicate that (-)Epicatechin gallate binds to the cell membrane in methicillin-resistant Staphylococcus aureus which decreases the fluidity of the bilayer and induces changes in gene expression.
别名表儿茶素没食子酸酯;ECG;(-)-cis-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol 3-gallate;(-)-cis-3,3′,4′,5,7-Pentahydroxyflavane 3-gallate;(-)-Epicatechin-3-O-gallate
Reaxys-RN1424379
Merck Index1090
标识符号https://www.aladdin-e.com/images/ghs/ghs07.jpg
信号词Warning
危害声明H315,H319,H335
警示性声明P261,P305+P351+P338
个人防护设备dust mask type N95 (US),Eyeshields,Gloves
RTECSDC7452000
WGK德国2
闪点(摄氏)160℃
风险声明 (欧洲)R36/37/38
安全声明(欧洲)S37/39
危害码(欧洲)Xi
搜索质检报告(COA)
搜索MSDS
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