熔点 | 255°C(lit.) |
敏感性 | 对热敏感 |
溶解性 | Soluble in water (5 mg/ml) with heat and sonication as needed, yielding a clear, colorless solution, ethanol (~1 mg/ml), methanol (sparingly), DMSO (~10 mg/ml), and DMF (~14 mg/ml). |
存贮条件 | 储存温度2-8℃ |
应用 | An antioxidant investigated as an adjunct treatment of some methyicillin resistant bacteria. |
生化机理 | (-)Epicatechin gallate is a polyphenol apoptosis inducer in tumor cells commonly found in green tea. Studies suggest that (-)Epicatechin gallate causes anti-proliferative and anti-inflammatory effects on pancreatic ductal adenocarcinoma cells. Alternate studies show that (-)Epicatechin gallate can suppress H2O2-induced genotoxicity in vitro in C6 astroglial cells. In contrast at high concentrations polyphenols are shown to reverse the genoprotective effects that they produce at low concentrations. Furthermore, (-)Epicatechin gallate can inhibit the development of mouse blastocysts via apoptosis. Studies indicate that (-)Epicatechin gallate binds to the cell membrane in methicillin-resistant Staphylococcus aureus which decreases the fluidity of the bilayer and induces changes in gene expression. |
别名 | 表儿茶素没食子酸酯;ECG;(-)-cis-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol 3-gallate;(-)-cis-3,3′,4′,5,7-Pentahydroxyflavane 3-gallate;(-)-Epicatechin-3-O-gallate |
(-)-表儿茶素没食子酸酯
(-)-Epicatechin gallate (订货以英文为准)
编号:E101659
CAS号:1257-08-5
分子式:C22H18O10
分子量:442.38
产品名称 | (-)-Epicatechin gallate |
中文名称 | (-)-表儿茶素没食子酸酯 |
CAS号 | 1257-08-5 |
分子式(M.F.) | C22H18O10 |
分子量(M.W.) | 442.38 |
储存条件 | 2-8°C储存 |
Reaxys-RN | 1424379 |
Merck Index | 1090 |
标识符号 | https://www.aladdin-e.com/images/ghs/ghs07.jpg |
信号词 | Warning |
危害声明 | H315,H319,H335 |
警示性声明 | P261,P305+P351+P338 |
个人防护设备 | dust mask type N95 (US),Eyeshields,Gloves |
RTECS | DC7452000 |
WGK德国 | 2 |
闪点(摄氏) | 160℃ |
风险声明 (欧洲) | R36/37/38 |
安全声明(欧洲) | S37/39 |
危害码(欧洲) | Xi |
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