| 溶解性 | Soluble in DMSO (100 mg/mL at 25 °C), water (23 mg/mL at 25 °C), ethanol (<1 mg/mL at 25 °C), and methanol. |
| 存贮条件 | 储存温度-20°C |
| 应用 | A modulator of Pgp. |
| 产品介绍 | Zosuquidar (LY335979) 3HCl是一种有效的P-glycoprotein（P-糖蛋白）介导的多药耐抗性的调节剂，Ki为60 nM。Phase 3。 |
| 备注 | Zosuquidar (LY335979) is a potent modulator of P-glycoprotein-mediated multi-drug resistance with Ki of 60 nM. Phase 3. |
| 生化机理 | Zosuquidar trihydrochloride is a potent modulator of P-glycoprotein-mediated(Mdr-1) multidrug resistance. This compound exhibits an IC50=60 nM. Zosuquidar trihydrochloride competitively inhibits equillibrium binding of drugs to Mdr-1 and shows an ability to reverse drug resistance to multiple oncolytics. |
| 别名 | Zosuquidar 三盐酸盐;(2R)-1-{4-[(1aR,6r,10bS)-1,1-二氟-1,1a,6,10b-四氢二苯并[a,e]环丙并[c]环庚烯-6-基]哌嗪-1-基}-3-(喹啉-5-基氧基)丙-2-醇三盐酸盐;RS 33295-198; Zosuquidar trihydrochloride;LY335979;LY-335979; (2R)-1-{4-[(1aR,6r,10bS)-1,1-Difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]cyclohepten-6-yl]piperazin-1-yl}-3-(quinolin-5-yloxy)propan-2-ol trihydrochloride;(2R)-Anti-5-[3-[4-(10,11-difluoromethanodibenzosuber-5-yl)piperazin-1-yl]-2-hydroxypropoxy]quinoline hydrochloride |
唑喹达三盐酸盐
Zosuquidar trihydrochloride （订货以英文为准）
编号：L126616
CAS号：167465-36-3
分子式：C32H31F2N3O2.3HCL
分子量：637.00
| 产品名称 | Zosuquidar trihydrochloride |
| 中文名称 | 唑喹达三盐酸盐 |
| CAS号 | 167465-36-3 |
| 分子式（M.F.） | C32H31F2N3O2.3HCL |
| 分子量（M.W.） | 637.00 |
| 储存条件 | -20°C储存 |
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