应用 | WAY-100635 maleate salt has been used as a 5-HT1A serotonin receptor antagonist:· to study whether the behavior of the cleaner wrasse is regulated by serotonin activity· to block activity of 3,4 methylenedioxymethamphetamine (MDMA) used to induce oxytocin release in male Wistar rats to increase their social behavior· to study the role of serotonin during metamorphosis of the ascidian Phallusia mammillata larvae |
产品介绍 | WAY-100635马来酸盐是5-HT受体拮抗剂,IC50为0.95nM |
生化机理 | WAY-100635 maleate salt is a potent, selective and high affinity SR-2B antagonist with a pIC50 of 10.4. The affinity (pKi) of WAY-100635 maleate salt for tSR-2B is 9.5. In addition, WAY-100635 maleate salt also blocks serotonin-evoked contraction of rat isolated stomach fundus. |
别名 | N- [2- [4-(2-甲氧基苯基)-1-哌嗪基] 乙基]-N-2-吡啶基环己基甲酰胺 马来酸盐;N-[2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinylcyclohexanecarboxamide maleate salt |
WAY-100635 马来酸盐
WAY-100635 maleate salt (订货以英文为准)
编号:W139124
CAS号:634908-75-1
分子式:C29H38N4O6
分子量:538.64
产品名称 | WAY-100635 maleate salt |
中文名称 | WAY-100635 马来酸盐 |
CAS号 | 634908-75-1 |
分子式(M.F.) | C29H38N4O6 |
分子量(M.W.) | 538.64 |
储存条件 | 2-8°C储存 |
WGK德国 | 3 |
闪点(摄氏) | 104 °C |
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