| 敏感性 | 对光敏感 |
| 溶解性 | Soluble in ethanol (1 mg/ml,stable at least a week at 4°C.), DMSO (10 mg/ml,stable at least six weeks at -20°C.), and methanol (10 mg/ml). Insoluble in water. |
| 存贮条件 | 储存温度2-8°C |
| 密度 | 1.2200 |
| 应用 | A novel tetracyclic diterpene antibiotic and also a DNA synthesis inhibitor in eukaryotes |
| 产品介绍 | Aphidicolin is a tetracyclic diterpene antibiotic and DNA synthesis inhibitor isolated from Cephalosporium aphidicola. Aphidicolin is reported to specifically inhibit DNA polymerase α and δ via binding to the enzyme, in eukaryotic cells such as the HeLa cell line, without affecting other DNA polymerases. This compound blocks the cell cycle at early S phase and has been reported to be useful for synchronizing cell cycles in cultured eukaryotic cells. This compound is also noted to induce apoptosis in HeLa S3 cells after 18-24 hours of the cell cycle. |
| 别名 | Aphidicolin;APC |
艾菲地可宁
Aphidicolin （订货以英文为准）
编号：A102398
CAS号：38966-21-1
分子式：C20H34O4
分子量：338.48
| 产品名称 | Aphidicolin |
| 中文名称 | 艾菲地可宁 |
| CAS号 | 38966-21-1 |
| 分子式（M.F.） | C20H34O4 |
| 分子量（M.W.） | 338.48 |
| 储存条件 | 2-8°C储存 |
| UN代码 | 3462 |
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