| 别名 | ;['4-(Diethylphosphonomethyl)cumene', '1-(Diethylphosphonomethyl)-4-isopropylbenzene', '(4-Isopropylbenzyl)phosphonic Acid Diethyl Ester'] |
(4-异丙基苄基)膦酸二乙酯
Diethyl (4-Isopropylbenzyl)phosphonate （订货以英文为准）
编号：D155194
CAS号：77237-55-9
分子式：C14H23O3P
分子量：270.30
| 产品名称 | Diethyl (4-Isopropylbenzyl)phosphonate |
| 中文名称 | (4-异丙基苄基)膦酸二乙酯 |
| CAS号 | 77237-55-9 |
| MDL编码 | D155194 |
| 分子式（M.F.） | C14H23O3P |
| 分子量（M.W.） | 270.30 |
| Reaxys-RN | 4169778 |
技术规格
| Background: | Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK. |
| Applications: | WB, IHC, IF |
| Name of antibody: | MAP3K5 |
| Immunogen: | Synthetic peptide of human MAP3K5 (Ab-83) |
| Full name: | mitogen-activated protein kinase kinase kinase 5 |
| Synonyms： | ASK1; MEKK5; MAPKKK5 |
| SwissProt: | Q99683 |
| IHC positive control: | Human breast carcinoma |
| IHC Recommend dilution: | 50-100 |
| WB Predicted band size: | 155 kDa |
| WB Positive control: | MDA-MB-435 cells |
| WB Recommended dilution: | 500-1000 |
| IF Positive control: | Hela cells |
| IF Recommended dilution | 100-200 |
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