1,2-二油酰-SN-甘油-3-磷酰乙醇胺 PEG 马来酰亚胺, DOPE-PEG-Mal

产品编号:D163573 品牌:阿拉丁,BBI
产品特点:
货号 包装 规格 目录价 您的价格 库存 数量 购买
D163573-50mg 50mg MW 2000 Da ¥452.90
D163573-250mg 250mg MW 2000 Da ¥1389.90
D163573-0100 100ul ¥1500.00
D163573-0025 25ul ¥400.00
D163573-0200 200ul ¥2500.00
溶解性Off-white/white solid or viscous liquid depends on molecule weight;Soluble in regular aqeous solution as well as most organic solvents;
产品介绍1,2-Dioleoyl-sn-Glycero-3-Phosphoethanolamine (DOPE) conjugated Polyethylene Glycol, DOPE PEG is an unsaturated C18 phospholipid PEG conjugate which has both hydrophilicity and hydrophobility. Pegylated phospholipids are excellent liposome formation materials that can be used for drug delivery, gene transfection and vaccine delivery as well. Pegylation of phospholipids significantly improves the blood circulation time and stability for encapsulated drugs. These materials can also be used for targeted drug delivery by modifying their surfaces with targeting ligands such as antibodies, peptides.
别名;

技术规格

Background: Atg2A (TG2 autophagy related 2 homolog A) is a 1,938 amino acid protein that belongs to the ATG2 family and may play a role in vesicle assembly. Encoded by a gene that maps to human chromosome 11q13.1, Atg2A is conserved in chimpanzee, dog, cow, mouse and rat, and exists as four alternatively spliced isoforms. Undetected in adult tissues, including heart, brain, placenta, lung, liver and skeletal muscle, Atg2A regulation may act as a distinct indicator of autophagic programmed cell death. Atg2A is upregulated in both etoposide- and doxorubicin-induced apoptosis of HeLa cells, suggesting that Atg2A functions as a novel biomarker of topoisomerase II inhibitor-mediated apoptosis. Atg2A associates with Atg2B, indicating that these two related proteins also functionally interact. Atg2A frameshift mutations are linked to gastric and colorectal carcinomas with high microsatellite instability and may contribute to cancer development by deregulating the autophagy process. Required for both autophagosome formation and regulation of lipid droplet morphology and dispersion.
Applications: ELISA, IHC
Name of antibody: ATG2A
Immunogen: Synthetic peptide of human ATG2A
Full name: autophagy related 2A
SwissProt: Q2TAZ0
ELISA Recommended dilution: 5000-10000
IHC positive control: Human gastric cancer
IHC Recommend dilution: 20-100
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