| 熔点 | 192-196℃ |
| 敏感性 | 对热和光线敏感 |
| 溶解性 | DMSO 100 mg/ml 1eq. HCl 100 mg/ml;Soluble in Acetronitrile |
| 存贮条件 | 储存温度-20°C |
| 应用 | A D2DR and serotonin inhibitor.Olanzapine may be used as a secondary pharma standard for the determination of the analyte in pharmaceutical formulations using high-performance liquid chromatography and spectrophotometric technique. These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| 产品介绍 | Olanzapine是一种高亲和力的5-HT2 5-羟色胺和多巴胺D2受体拮抗剂。Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Olanzapine is an atypical antipsychotic drug, widely used for the treatment of acute schizophrenia and psychotic conditions. |
| 备注 | Olanzapine is a high affinity for 5-HT2 serotonin and D2 dopamine receptor antagonist. |
| 生化机理 | Olanzapine(Zyprexa) is a high affinity for 5-HT2 serotonin and D2 dopamine receptor antagonist. It has a higher affinity for 5-HT2 serotonin receptors than D2 dopamine receptors. Like most atypical antipsychotics, compared to the older typical ones, olanzapine has a lower affinity for histamine, cholinergic muscarinic and alpha adrenergic receptors. Olanzapine also exhibits weak affinity for GABAA, BZD receptor site which may contribute slightly to its sedating properties. Antagonizing H1 histamine receptors causes sedation and may cause weight gain, although antagonistic actions at 5-HT2C receptors have also been implicated in weight gain. |
| 别名 | Zyprexa, Zalasta, Zolafren, Olzapin, Oferta, Zypadhera;奥氮平;2-甲基-4-(4-甲基-1-哌嗪基)-10H-噻吩并[2,3-b][1,5]苯并二氮杂;Zyprexa;LY170053;LY-170053;LY 170053;2-Methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine;Lanzac |
奥氮平
Olanzapine （订货以英文为准）
编号：O126519
CAS号：132539-06-1
分子式：C17H20N4S
分子量：312.44
| 产品名称 | Olanzapine |
| 中文名称 | 奥氮平 |
| CAS号 | 132539-06-1 |
| 分子式（M.F.） | C17H20N4S |
| 分子量（M.W.） | 312.44 |
| 储存条件 | 避光;-20°C储存 |
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