熔点 | 300℃ |
敏感性 | 对光线敏感 |
溶解性 | Soluble in dilute ammonia water,trimethylamine, p-toluidine, dimethylaniline and 0.1-1.0 N NaOH. Insoluble in water. |
存贮条件 | 储存温度2-8℃ |
应用 | 营养增补剂(铁质强化剂),是从猪血中提取的,现代医学公认的防治缺铁性贫血、吸收率高、效果好的往下生物铁源,无铁腥味,不刺激肠胃。是生产天然补铁食品、药品、保健品、化妆品的首选原料。 高铁血红素应用于以下应用中:· 研究菌株和生长条件· 用于短期菌落测定(培养基由血红素和其他成分组成)· 细胞转染它可用于分析MMV(抗疟药物)疟疾盒化合物对β-血红蛋白形成的抑制作用。 |
产品介绍 | Hemin chloride, a heme oxygenase 1 inducer, is a porphyrin complex that is derived from erythrocytes. At a concentration of 20 mM Hemin chloride demonstrated the significance of heme in myotube maturation by increasing size, number, cross-striations, and contraction frequency and strength of myotubes. The compound has been observed to induce cGMP formation through induction of guanylate cyclase. Hemin chloride has been noted to stimulate calcium-dependent K+ channels and modulate fluid transport and Na+ in the loop of henle in rat studies. Hemin has also been documented to give rise to active chloride secretion in Caco-2 cells. In cadmium injured rat testes, hemin chloride demonstrated anti-apoptotic, antiinflamatory and antioxidant properties. Through reactive oxygen species of ERK-1/2-Elk-1 and NF-κB, hemin chloride has been shown to upregulate Egr-1 expression in vascular smooth muscle cells. It has also been used in solution to prepare agar medium for the cultivation of distinct bacteria. |
生化机理 | 高铁血红素是经氧化血红素,是一系列蛋白质的一种含铁的辅基基团。游离血红素在溶血后从血红蛋白中释放出来,具有促炎作用,有助于铁源活性氧的生成。游离血红素水平可在各种病理条件下上调,并可导致各种炎症条件,包括血管疾病、肾功能衰竭和免疫介导的疾病。高铁血红素可用于研究血红素加氧酶1 (HO-1)的表达和抑制以及HO-1的活性。 血凝素是生长流感嗜血杆菌所必需的“X因子”. |
别名 | 血晶素;卟啉铁;血晶质;亚铁原卟啉;氯高铁血红素;水溶性氯化血红素;氯(原卟啉酸)铁(III), 氯原卟啉IX铁(III), 高铁原卟啉IX氯, 高铁血红素(氯);Teichmann's crystals; Ferriheme chloride; Chloroferriprotoporphyrin; Chloro(protoporphyrinato)iron(III);Chlorohemin Chloroprotoporphyrin IX iron(III);Ferriprotoporphyrin IX chloride;Hemin(chloride); |
氯化血红素
Hemin (订货以英文为准)
编号:H140872
CAS号:16009-13-5
分子式:C34H34CLFEN4O4
分子量:653.96
产品名称 | Hemin |
中文名称 | 氯化血红素 |
CAS号 | 16009-13-5 |
分子式(M.F.) | C34H34CLFEN4O4 |
分子量(M.W.) | 653.96 |
储存条件 | 2-8°C储存 |
个人防护设备 | Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter |
WGK德国 | 3 |
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