| 溶解性 | DMSO 89 mg/mL Water <1 mg/mL Ethanol <1 mg/mL |
| 存贮条件 | 储存温度-20°C |
| 产品介绍 | Canagliflozin inhibits Na+- dependent 14C-AMG uptake in a concentration-dependent fashion. It is a novel C-glucoside with thiophene ring. |
| 备注 | Canagliflozin is a highly potent and selective SGLT2 inhibitor for hSGLT2 with IC50 of 2.2 nM, exhibits 413-fold selectivity over hSGLT1. |
| 生化机理 | Canagliflozin(JNJ 24831754ZAE; JNJ 28431754; JNJ 28431754AAA; TA 7284) is an experimental drug being developed by Johnson & Johnson for the treatment of type 2 diabetes.Canagliflozin(JNJ 24831754ZAE; JNJ 28431754; JNJ 28431754AAA; TA 7284) is an inhibitor of subtype 2 sodium-glucose transport protein (SGLT2), which is responsible for at least 90% of the glucose reabsorption in the kidney. Blocking this transporter causes blood glucose to be eliminated through the urine. |
| 别名 | 坎格列净;(1S)-1,5-脱氢-1-C-[3-[[5-(4-氟苯基)-2-噻吩基]甲基]-4-甲基苯基]-D-葡萄糖醇;JNJ 24831754ZAE; JNJ 28431754; JNJ 28431754AAA; TA 7284;(2S,3R,4R,5S,6R)-2-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)-6-(hydroxymethyl)-tetrahydro-2H-pyran-3,4,5-triol |
卡格列净
Canagliflozin （订货以英文为准）
编号：C126191
CAS号：842133-18-0
分子式：C24H25FO5S
分子量：444.52
| 产品名称 | Canagliflozin |
| 中文名称 | 卡格列净 |
| CAS号 | 842133-18-0 |
| 分子式（M.F.） | C24H25FO5S |
| 分子量（M.W.） | 444.52 |
| 储存条件 | -20°C储存 |
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