卡培他滨

Capecitabine (订货以英文为准)

编号:C124969
CAS号:154361-50-9
分子式:C15H22FN3O6
分子量:359.35
货号 品牌 包装 目录价 您的价格 库存 数量 购买
C124969-1g 阿拉丁 1g ¥55.90
C124969-5g 阿拉丁 5g ¥86.90
C124969-250mg 阿拉丁 250mg ¥29.90
C124969-25g 阿拉丁 25g ¥234.90
C124969-100g 阿拉丁 100g ¥668.90
产品名称 Capecitabine
中文名称 卡培他滨
CAS号 154361-50-9
分子式(M.F.) C15H22FN3O6
分子量(M.W.) 359.35
储存条件 -20°C储存
溶解性Soluble in water (26 mg/ml), ethanol (207 mg/ml), methanol (> 40%), DMF (~14 mg/ml), and DMSO (72 mg/ml at 25 °C).
存贮条件储存温度-20°C
应用An antiproliferative 5-fluorouracil releasing compound
产品介绍Capecitabine是一种治疗肿瘤选择性的氟嘧啶氨基甲酸酯,具有较高的瘤内5-FU水平,且毒性比5-FU低。
备注Capecitabine is a tumor-selective fluoropyrimidine carbamate which achieves higher intratumoral 5-FU level with lower toxicity than 5-FU.
生化机理Capecitabine is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and colorectal cancers. Capecitabine is a prodrug, that is enzymatically converted to 5-fluorouracil in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue. The activation of capecitabine follows a pathway with three enzymatic steps and two intermediary metabolites, 5'-deoxy-5-fluorocytidine (5'-DFCR) and 5'-deoxy-5-fluorouridine (5'-DFUR), to form 5-fluorouracil. From Wikipedia.
别名卡培他滨;5'-脱氧-5-氟-N4-[(戊氧基)羰基]胞啶;Ro-9-1978;5′-Deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine;5'-Deoxy-5-fluoro-N4-[((pentyloxy)carbonyl]cytidine
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