溶解性 | DMSO 18 mg/mL Water <1 mg/mL Ethanol <1 mg/mL |
存贮条件 | 储存温度-20°C |
产品介绍 | Apixaban是一种高度选择性,可逆的凝血因子 Xa 抑制剂,抑制人和兔凝血因子 Xa 的 Ki 值分别为 0.08 nM 和 0.17 nM。Apixaban 正在开发用于预防和治疗各种血栓栓塞疾病。 |
备注 | Apixaban is a highly selective, reversible inhibitor of Factor Xa with Ki of 0.08 nM and 0.17 nM in human and rabbit, respectively. |
生化机理 | Apixaban(BMS-562247-01; BMS 562247-01) is a direct factor Xa inhibitor with an IC50 of 0.22±0.02 μM. Apixaban is a compound being investigated as an anticoagulant. Apixaban (BMS-562247-01; BMS 562247-01)has similar affinity for human and rabbit factor Xa (FXa). |
别名 | 阿哌沙班; 4,5,6,7-四氢-1-(4-甲氧基苯基)-7-氧代-6-[4-(2-氧代-1-哌啶基)苯基]-1H-吡唑并[3,4-C]吡啶-3-甲酰胺;BMS-562247-01; BMS 562247-01; BMS562247-01;1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide |
阿哌沙班
Apixaban (订货以英文为准)
编号:A126046
CAS号:503612-47-3
分子式:C25H25N5O4
分子量:459.50
产品名称 | Apixaban |
中文名称 | 阿哌沙班 |
CAS号 | 503612-47-3 |
分子式(M.F.) | C25H25N5O4 |
分子量(M.W.) | 459.50 |
储存条件 | -20°C储存 |
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