| 熔点 | 262°C |
| 溶解性 | Soluble in water (partly), DMSO (50 mg/ml), DMF (1 mg/ml), 1eq. HCl (50 mM), and dilute alkalies. |
| 应用 | An antiviral compound that can be used to induce apoptosis. |
| 产品介绍 | Acyclovir 是一种合成的核苷类似物，有效作用于疱疹病毒。 |
| 备注 | Acyclovir is a synthetic nucleoside analogue active against herpesviruses. |
| 生化机理 | Acyclovir is an antiviral compound that can be used to induce apoptosis in cells transfected with herpes simplex virus thymidine kinase (HSV-TK). The compound may exert inhibitory effects through the alterations of the cell cycle in leukemia cells lines, such as p185BCR-ABL expressing OM9;22 cells, by synchronizing the G0/G1 phase. Formation of acycloguanosine triphosphate occurs through the phosphorylation of HSV-TK and can inhibit the viral DNA polymerase. Acyclovir also has the ability to inhibit the proliferation of the fibroblast cells, NIH 3T3, transformed with v-abl or bcr-abl. |
| 别名 | 阿昔洛韦;无环鸟苷;无环鸟嘌呤核苷;9-[(2-羟基乙氧基)甲基]鸟嘌呤;Acycloguanosine;9-[(2-Hydroxyethoxy)methyl]guanine;9-[(2-Hydroxyethoxy)methyl]guanine;2-Amino-1,9-dihydro-9-((2-hydroxyethoxy)methyl)-6H-purin-6-one;2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one |
阿昔洛韦
Aciclovir （订货以英文为准）
编号：A126073
CAS号：59277-89-3
分子式：C8H11N5O3
分子量：225.20
| 产品名称 | Aciclovir |
| 中文名称 | 阿昔洛韦 |
| CAS号 | 59277-89-3 |
| 分子式（M.F.） | C8H11N5O3 |
| 分子量（M.W.） | 225.20 |
| 储存条件 | -20°C储存 |
| Reaxys-RN | 3922496 |
| 个人防护设备 | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
| RTECS | UA0600000 |
| WGK德国 | 3 |
| 风险声明 (欧洲) | R36/37/38 |
| 安全声明（欧洲） | S26;S37/39 |
| 危害码（欧洲） | Xi |
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