阿夫唑嗪盐酸盐

Alfuzosin hydrochloride (订货以英文为准)

编号:A129804
CAS号:81403-68-1
分子式:C19H28CLN5O4
分子量:425.91
货号 品牌 包装 目录价 您的价格 库存 数量 购买
A129804-25mg 阿拉丁 25mg ¥121.90
A129804-100mg 阿拉丁 100mg ¥211.90
A129804-1g 阿拉丁 1g ¥966.90
A129804-250mg 阿拉丁 250mg ¥387.90
A129804-50mg 阿拉丁 50mg ¥154.90
A129804-5g 阿拉丁 5g ¥2966.90
产品名称 Alfuzosin hydrochloride
中文名称 阿夫唑嗪盐酸盐
CAS号 81403-68-1
MDL编码 MFCD00879135
分子式(M.F.) C19H28CLN5O4
分子量(M.W.) 425.91
溶解性Soluble in DMSO (85 mg/ml at 25 °C), methanol, ethanol (85 mg/ml at 25 °C), and PBS (pH 7.2) (~1 mg/ml). Insoluble in water.
应用An α 1 adrenoceptor antagonist.
产品介绍Alfuzosin HCl 是一种α1受体拮抗剂,用于治疗良性前列腺增生(BPH)。
备注Alfuzosin(Uroxatral) is an alpha1 receptor antagonist used to treat benign prostatic hyperplasia (BPH).
生化机理Alfuzosin hydrochloride is a uro-selective α 1 adrenoceptor antagonist that does not distinguish between α 1 subtypes. In addition, in vitro studies indicate that Alfuzosin hydrochloride can relax corpus cavernosum tissue. Also Alfuzosin hydrochloride has been seen to inhibit the increase of intraurethral pressure caused by phenylephrine. Studies suggest that isocratic reversed phase high-performance liquid chromatographic (HPLC) with ultraviolet detection at 245 nm can be used, along with a stainless steel analytical column to determine the presence of Alfuzosin hydrochloride in solution. Furthermore, alternate studies indicate that Alfuzosin hydrochloride can be detected in human plasma using a spectrofluorimetric method which relies on measuring the native fluorescence of Alfuzosin hydrochloride in deionized water using λ excitation at 325.0 nm and λ emission at 390.0 nm along with solid phase extraction.
别名阿夫唑嗪盐酸盐; N-[3-[(4-氨基-6,7-二甲氧基-2-喹唑啉基)(甲基)氨基]丙基]四氢-2-呋喃酰胺盐酸盐;4-氨基-6,7-二甲氧基-2-[甲基[3-[(四氢-2-呋喃甲酰)氨基]丙基]氨基]喹唑啉盐酸盐;盐酸阿夫唑嗪;N-(3-((4-Amino-6,7-dimethoxy-2-quinazolinyl)methylamino)propyl)tetrahydro-2-furancarboxamide hydrochloride; Uroxatral hydrochloride;4-Amino-6,7-dimethoxy-2-[methyl[3-[(tetrahydro-2-furoyl)amino]propyl]amino]quinazoline Hydrochloride;Alfuzosin HCl
WGK德国3
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