溶解性 | Soluble in water (4-5 mg/ml), and methanol. |
存贮条件 | 储存温度 2-8°C |
应用 | A sulfate salt form of atazanavir that is an highly potent HIV-1 protease inhibitor. |
产品介绍 | Atazanavir Sulfate是一种HIV protease(HIV蛋白酶)抑制剂,抑制HIV Atazanavir,Ki值为2.66 nM。 |
备注 | Atazanavir is a HIV protease inhibitor with Ki of 2.66 nM. |
生化机理 | Atazanavir sulfate is a sulfate salt form of atazanavir that is an highly potent HIV-1 protease inhibitor. Has shown to be generally more potent than the five currently approved HIV-1 Prt inhibitors. Atazanavir (BMS-232632) inhibited the proteolytic cleavage of the viral gag precursor p55 polyprotein in a dose-dependent manner, with a EC50 of approximately 47 nM. Also highly selective for HIV-1 Prt and exhibits cytotoxicity only at concentrations 6,500- to 23,000-fold higher than that required for anti-HIV activity. Atazanavir (BMS-232632) may be an effective HIV-1 inhibitor that may be utilized in a variety of different drug combinations. |
别名 | BMS-232632-05;阿扎那韦硫酸盐;BMS-232632-05; Reyataz;BMS 232632 sulfate; BMS-232632 sulfate; BMS232632 sulfate;Methyl N-[(2S)-1-[[(2S,3S)-3-hydroxy-4-[[[(2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoyl]amino]-[(4-pyridin-2-ylphenyl)methyl]amino]-1-phenylbutan-2-yl]amino]-3,3-dimethyl-1-oxobutan-2-yl]carbamate sulfate |
阿扎那韦硫酸盐
Atazanavir Sulfate (订货以英文为准)
编号:A129321
CAS号:229975-97-7
分子式:C38H52N6O7.H2SO4
分子量:802.93
产品名称 | Atazanavir Sulfate |
中文名称 | 阿扎那韦硫酸盐 |
CAS号 | 229975-97-7 |
分子式(M.F.) | C38H52N6O7.H2SO4 |
分子量(M.W.) | 802.93 |
储存条件 | 2-8°C储存;充氩 |
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