阿扎那韦硫酸盐

Atazanavir Sulfate (订货以英文为准)

编号:A129321
CAS号:229975-97-7
分子式:C38H52N6O7.H2SO4
分子量:802.93
货号 品牌 包装 目录价 您的价格 库存 数量 购买
A129321-1g 阿拉丁 1g ¥144.90
A129321-50mg 阿拉丁 50mg ¥72.90
A129321-5mg 阿拉丁 5mg ¥41.90
A129321-250mg 阿拉丁 250mg ¥81.90
A129321-10mg 阿拉丁 10mg ¥51.90
A129321-5g 阿拉丁 5g ¥560.90
A129321-25g 阿拉丁 25g ¥1721.90
产品名称 Atazanavir Sulfate
中文名称 阿扎那韦硫酸盐
CAS号 229975-97-7
分子式(M.F.) C38H52N6O7.H2SO4
分子量(M.W.) 802.93
储存条件 2-8°C储存;充氩
溶解性Soluble in water (4-5 mg/ml), and methanol.
存贮条件储存温度 2-8°C
应用A sulfate salt form of atazanavir that is an highly potent HIV-1 protease inhibitor.
产品介绍Atazanavir Sulfate是一种HIV protease(HIV蛋白酶)抑制剂,抑制HIV Atazanavir,Ki值为2.66 nM。
备注Atazanavir is a HIV protease inhibitor with Ki of 2.66 nM.
生化机理Atazanavir sulfate is a sulfate salt form of atazanavir that is an highly potent HIV-1 protease inhibitor. Has shown to be generally more potent than the five currently approved HIV-1 Prt inhibitors. Atazanavir (BMS-232632) inhibited the proteolytic cleavage of the viral gag precursor p55 polyprotein in a dose-dependent manner, with a EC50 of approximately 47 nM. Also highly selective for HIV-1 Prt and exhibits cytotoxicity only at concentrations 6,500- to 23,000-fold higher than that required for anti-HIV activity. Atazanavir (BMS-232632) may be an effective HIV-1 inhibitor that may be utilized in a variety of different drug combinations.
别名BMS-232632-05;阿扎那韦硫酸盐;BMS-232632-05; Reyataz;BMS 232632 sulfate; BMS-232632 sulfate; BMS232632 sulfate;Methyl N-[(2S)-1-[[(2S,3S)-3-hydroxy-4-[[[(2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoyl]amino]-[(4-pyridin-2-ylphenyl)methyl]amino]-1-phenylbutan-2-yl]amino]-3,3-dimethyl-1-oxobutan-2-yl]carbamate sulfate
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