| 敏感性 | 对光线敏感 |
| 别名 | 2,6-二溴-1,4,5,8-萘四甲酸1,8:4,5-二酐; |
2,6-二溴萘-1,4,5,8-四甲酸二酐
2,6-Dibromonaphthalene-1,4,5,8-tetracarboxylic Dianhydride （订货以英文为准）
编号：D155087
CAS号：83204-68-6
分子式：C14H2BR2O6
分子量：425.97
| 产品名称 | 2,6-Dibromonaphthalene-1,4,5,8-tetracarboxylic Dianhydride |
| 中文名称 | 2,6-二溴萘-1,4,5,8-四甲酸二酐 |
| CAS号 | 83204-68-6 |
| 分子式（M.F.） | C14H2BR2O6 |
| 分子量（M.W.） | 425.97 |
| 储存条件 | 充氩 |
技术规格
| Background: | A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene. |
| Applications: | WB, IHC |
| Name of antibody: | BCR (Phospho-Tyr177) |
| Immunogen: | Synthetic peptide of human BCR (Phospho-Tyr177) |
| Full name: | breakpoint cluster region (Phospho-Tyr177) |
| Synonyms： | ALL; CML; PHL; BCR1; D22S11; D22S662 |
| SwissProt: | P11274 |
| IHC positive control: | Human tonsil tumor |
| IHC Recommend dilution: | 50-100 |
| WB Predicted band size: | 210 kDa |
| WB Positive control: | K562 cells untreated or treated with H2O2 |
| WB Recommended dilution: | 500-1000 |
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