2-豆蔻酸锡酰-3-磷脂乙醇胺 PEG N-羟基琥珀酰亚胺

产品编号:D163568 品牌:阿拉丁,BBI
产品特点:
货号 包装 规格 目录价 您的价格 库存 数量 购买
D163568-500mg 500mg MW 5000 Da ¥2200.90
D163568-100mg 100mg MW 5000 Da ¥569.90
D163568-0100 100ul ¥1500.00
D163568-0025 25ul ¥400.00
D163568-0200 200ul ¥2500.00
溶解性Off-white/white solid or viscous liquid depends on molecule weight;Soluble in regular aqeous solution as well as most organic solvents;
产品介绍1,2-Dimyristoyl-sn-Glycero-3-Phosphoethanolamine (DMPE) conjugated Polyethylene Glycol, DMPE PEG is a phospholipid PEG conjugate which has both hydrophilicity and hydrophobility. Pegylated phospholipids are excellent liposome formation materials that can be used for drug delivery, gene transfection and vaccine delivery as well. Pegylation of phospholipids significantly improves the blood circulation time and stability for encapsulated drugs. These materials can also be used for targeted drug delivery by modifying their surfaces with targeting ligands such as antibodies, peptides.
别名;

技术规格

Background: The transcriptional co-activator with PDZ-binding motif (TAZ) is a 14-3-3-binding molecule. The highly conserved and ubiquitously expressed 14-3-3 proteins regulate differentiation, cell cycle progression and apoptosis by binding intracellular phosphoproteins involved in signal transduction. TAZ may link events at the plasma membrane and cytosketeton to nuclear transcription in a manner that can be regulated by 14-3-3. TAZ shares homology with the WW domain of Yes-associated protein (YAP) and functions as a transcriptional co-activator by binding to the PPXY motif present on transcription factors. TAZ recognizes immunoreactive protein bands in lysates from MDCK, NIH-3T3 and 293T cells. In addition, COS7, Hep G2, CHO and HeLa cells express endogenous TAZ. 14-3-3 binding requires TAZ phosphorylation on a single Serine 89 residue, resulting in the inhibition of TAZ transcriptional co-activation through 14-3-3-mediated nuclear export.
Applications: ELISA, WB
Name of antibody: WWTR1
Immunogen: Synthetic peptide of human WWTR1
Full name: WW domain containing transcription regulator 1
Synonyms: TAZ
SwissProt: Q9GZV5
ELISA Recommended dilution: 5000-10000
WB Predicted band size: 44 kDa
WB Positive control: HEPG2, Jurkat, A431 and NIH/3T3 cell lysates
WB Recommended dilution: 200-1000
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