巴格列酮

Balaglitazone (订货以英文为准)

编号:B125827
CAS号:199113-98-9
分子式:C20H17N3O4S
分子量:395.43
货号 品牌 包装 目录价 您的价格 库存 数量 购买
B125827-5mg 阿拉丁 5mg ¥1321.90
B125827-50mg 阿拉丁 50mg ¥5405.90
B125827-10mg 阿拉丁 10mg ¥2349.90
产品名称 Balaglitazone
中文名称 巴格列酮
CAS号 199113-98-9
分子式(M.F.) C20H17N3O4S
分子量(M.W.) 395.43
储存条件 -20°C储存
溶解性25°C: DMSO
存贮条件储存温度-20°C
生化机理Description:IC50 Value: N/ABalaglitazone (DRF-2593) is a novel partial agonist of PPAR-gamma (γ), which is developed by Dr. Reddy's laboratories India. Balaglitazone is a second generation peroxisome proliferator-activated receptor (PPAR) gamma agonist with only partial agonistic properties.in vitro: The Rs for the separations were 3.5 for balaglitazone enantiomers, 3.5 for pioglitazone enantiomers, and 3.7 for rosiglitazone. The squared correlation coefficients (r2) were found to be 0.999 for all three compounds [1].in vivo: Balaglitazone treated groups shown significantly reduce of HbA1c (%), FSG (mmol/L), postprandial glucose as comparison to pioglitazone. Balaglitazone 10 mg and 20 mg show the similar magnitudes of the effects which comparable to the effects seen in the pioglitazone 45 mg group. The incidence of fluid retention and fat accumulation fewer than those observed with pioglitazone 45 mg [2]. Sixty male dio induced obese
别名DRF-2593;NN-2344;DRF2593;NN2344;DRF 2593;NN 2344;巴格列酮;DRF-2593;NN-2344;DRF2593;NN2344;DRF 2593;NN 2344;5-[[4-[[3-Methyl-4-oxo-3,4-dihydro-2-quinazolinyl]methoxy]phenyl]methyl]thiazolidine-2,4-dione
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