| 敏感性 | 对光敏感 |
| 溶解性 | Soluble in DMSO (> 25 mg/ml), ethanol (20 mg/ml), water (≤ 2 mg/ml), and methanol. |
| 应用 | An L-/N-type calcium channel protein inhibitor and blocker |
| 产品介绍 | Cilnidipine是一种钙离子通道抑制剂。It is a dual blocker of L-type voltage-gated calcium channels in vascular smooth muscle and N-type calcium channels in sympathetic nerve terminals that supply blood vessels. |
| 备注 | Cilnidipine is a calcium channel blocker. |
| 生化机理 | Cilnidipine is a dual L- and N-type calcium channel blocker and displays antihypertensive, sympatholytic and neuroprotective activity. Cilnidipine has displayed renal and vascular protective effects and improved baroreflex sensitivity in patients with hypertension. It has also demonstrated neuroprotective effects in a rat focal brain ischemia model by removing free radicals and activating the phosphatidylinositol 3-kinase pathway. |
| 别名 | FRC 8653;西尼地平;1,4-二氢-2,6-二甲基-4-(3-硝基苯基)-3,5-吡啶二羧酸2-甲氧基乙酯肉桂醇酯;FRC 8653;3-cinnamyl 5-(2-methoxyethyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate |
西尼地平
Cilnidipine （订货以英文为准）
编号：C125274
CAS号：132203-70-4
分子式：C27H28N2O7
分子量：492.52
| 产品名称 | Cilnidipine |
| 中文名称 | 西尼地平 |
| CAS号 | 132203-70-4 |
| MDL编码 | MFCD00865853 |
| 分子式（M.F.） | C27H28N2O7 |
| 分子量（M.W.） | 492.52 |
| 储存条件 | -20°C储存 |
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